Imaging-Guided Cancer Therapy Based on Multifunctional Magnetic Nanoparticles  

作　　者：Ran Ma Yanglong Hou Shuren Wang 

机构地区：[1]Beijing Key Laboratory of Magnetoelectric Materials and Devices,School of Materials Science and Engineering,Beijing Innovation Centre for Engineering Science and Advanced Technology,Peking University,Beijing,100871 China

出　　处：《Chinese Journal of Chemistry》2023年第19期2557-2573,共17页中国化学（英文版）

基　　金：support from the National Natural Science Foundation of China(52201198,52027801,and 51631001);the National Key R&D Program of China(2017YFA0206301);the China-Germany Collaboration Project(M-0199).

摘　　要：In recent years,magnetic nanoparticles(MNPs)have received great attention within the field of biomedicine,especially for cancer therapy.This is because MNPs have many excellent physical and chemical properties to provide sufficient imaging information along with satisfactory therapeutic efficacy.Moreover,by virtue of various modification strategies,the obtained multifunctional MNPs can further achieve synergized multimodal cancer theranostic,which is worthy of further study.In this review,we summarize the recent developments in imaging-guided strategies and synergistic cancer therapy based on multifunctional MNPs.Then,we discuss the challenge and perspective of the next generation of MNPs-based imaging-guided cancer therapy,hoping to provide guidance in potential applications.

关 键 词：CANCER Cancer therapy Modal imaging Magnetic nanoparticles Synergistic action NANOTECHNOLOGY Synthesis design DRUGDELIVERY Imagingagents 

分 类 号：R730.5[医药卫生—肿瘤]