副溶血性弧菌污染所致1起食源性疾病暴发事件的流行病学调查  

Epidemiological investigation of a foodborne illness outbreak caused by Vibrio parahaemolyticus contamination

作　　者：龙辉 潘杰[1] 李德成 王萧 熊峰 LONG Hui;PAN Jie;LI Decheng;WANG Xiao;XIONG Feng(Aijie Surveillance Section,Nanxun District Center for Disease Control and Prevention,Huzhou,Zhejiang 313009,China)

机构地区：[1]浙江省湖州市南浔区疾病预防控制中心艾结监测科,浙江湖州313009

出　　处：《上海预防医学》2023年第11期1118-1123,共6页Shanghai Journal of Preventive Medicine

摘　　要：【目的】调查和分析浙江省湖州市1起食源性疾病暴发事件的原因,为避免此类事件的发生提供依据。【方法】根据所制订的病例定义进行病例搜索。对事件进行现场流行病学调查,对病例组和对照组进行问卷调查。使用χ2检验、logistic回归分析食源性疾病暴发的影响因素。同时对采集的病例粪便标本、食物标本、环境标本、水标本进行实验室检测,对分离出的阳性菌株开展脉冲场凝胶电泳(PFGE)分子分型。【结果】事件同期暴露410人,可能病例18人,罹患率为4.39%。患者症状以腹痛、腹泻为主,伴有恶心、乏力、发热等症状。纳入病例组17例和对照组19例,病例对照分析结果提示,白灼深水虾(OR=19.42,95%CI=1.06~357.02,P=0.046)、蒜蓉粉丝蒸澳龙(OR=22.01,95%CI=1.24~390.70,P=0.035)为可疑食物。经实验室检测,5例病例副溶血性弧菌(VP)阳性,血清型均为O10∶K4;留样食物中蒜蓉粉丝蒸澳龙标本和羊排标本VP阳性,血清型为O5∶Kut。【结论】该事件是一起共同食用VP污染的婚宴所致的食源性疾病暴发事件,餐次为9月17日某酒店供应的晚餐。可疑食物为白灼深水虾和蒜蓉粉丝蒸澳龙。[Objective]In this paper,the cause of an outbreak of foodborne disease in Huzhou City was analyzed,which may help avoid the recurrence of such incidents.[Methods]Through the field epidemiological investigation,the case definition was formulated and the questionnaire survey was carried out in the case group and the control group.In addition,the chi-square test and logistic regression method were used to identify the factors affecting the outbreak.The patient stool samples,food samples,environmental samples and water samples were collected and used for the laboratory test.The PFGE molecular typing was conducted on the isolated positive strains.[Results]The number of people exposed during the same period was 410,and the number of possible cases was 18,with an incidence of 4.39%.Generally,the main symptoms were abdominal pain and diarrhea,accompanied by nausea,fatigue,fever and others.For case-control analysis,17 of the 18 patients were included in the case group,and 19 non-patients were into control group.The results suggested that the risk factors were blanched deep-water shrimp(OR=19.42,95%CI=1.06-357.02,P=0.046)and steamed Ao Long(Australian lobster)with garlic and vermicelli(OR=22.01,95%CI=1.24-390.70,P=0.035).According to the laboratory test results Vibrio parahaemolyticus(VP)was positive in 5 cases,and the serum type was is O10∶K4.In the reserved food,VP was positive in the samples of steamed Australian lobster with garlic vermicelli and lamb chops.The serum type was O5∶Kut.[Conclusion]This incident was an outbreak of foodborne disease caused by the consumption of wedding food contaminated by VP.The dinner was served by Hotel B on September 17.Moreover,the suspicious foods include the blanched deep-water shrimp and steamed lobster with garlic vermicelli.

关 键 词：副溶血性弧菌 食源性疾病 暴发 PFGE分子分型 流行病学调查 

分 类 号：R155[医药卫生—营养与食品卫生学]