Resveratrol combats chronic diseases through enhancing mitochondrial quality  

作　　者：Weichu Tao Hu Zhang Xia Jiang Ning Chen 

机构地区：[1]Tianjiu Research and Development Center for Exercise Nutrition and Foods,Hubei Key Laboratory of Exercise Training and Monitoring,College of Sports Medicine,Wuhan Sports University,Wuhan 430079,China [2]The University Hospital of Wuhan Sports University,Wuhan 430079,China

出　　处：《Food Science and Human Wellness》2024年第2期597-610,共14页食品科学与人类健康（英文）

基　　金：supported by the National Natural Science Foundation of China(No.32071176);the 14th Five-Year-Plan Advantageous and Characteristic Disciplines(Groups)of Colleges and Universities in Hubei Province for Exercise and Brain Science from Hubei Provincial Department of Education;the Chutian Scholar Program;Innovative Start-Up Foundation from Wuhan Sports University to Ning Chen。

摘　　要：Resveratrol(RSV),as a functional food component extracted from natural plants,has been widely studied and recognized in preventing and treating various diseases,with major mechanisms including executing anti-inflammation and anti-oxidation functions,and improving mitochondrial quality.Chronic diseases as non-communicable diseases are mainly caused by multiple factors,such as physiological decline and dysfunction in the body,and have become a significant challenge on public health worldwide.It is worth noting that chronic diseases such as Alzheimer's disease(AD),Parkinson's disease(PD),muscle atrophy,cardiovascular disease,obesity,and cancer are accompanied by abnormal mitochondrial function.Therefore,targeted regulation of mitochondria may be a meaningful way to prevent and treat chronic diseases.Increasing evidence has confirmed that RSV is actively involved in regulating mitochondria,and it has become an essential consideration to prevent and treat chronic diseases through targeting mitochondria and improving corresponding functions.In this article,current studies on RSV to optimize mitochondrial quality for preventing and alleviating chronic disease are systematically summarized,which can provide a theoretical reference for the development of functional foods or drugs to combat chronic diseases.

关 键 词：RESVERATROL Functional food Mitochondrial quality Chronic disease ANTI-INFLAMMATION ANTI-OXIDATION 

分 类 号：TS201.2[轻工技术与工程—食品科学] TQ460.1[轻工技术与工程—食品科学与工程]