Parotid metastasis of rare lung adenocarcinoma:A case report  

作　　者：Ru-Xi Yan Lin-Bo Dou Zi-Jia Wang Xue Qiao Hong-Hai Ji Yan-Cong Zhang 

机构地区：[1]School of Stomatology,Weifang Medical University,Weifang 261000,Shandong Province,China [2]Department of Stomatology,Dezhou People’s Hospital,Dezhou 253000,Shandong Province,China [3]Department of Stomatology,Dezhou Women and Children's Hospital,Dezhou 253000,Shandong Province,China

出　　处：《World Journal of Clinical Cases》2024年第6期1182-1189,共8页世界临床病例杂志

摘　　要：BACKGROUND Lung cancer(LC)is the leading cause of malignancy-related deaths worldwide.The most common sites of metastasis include the nervous system,bone,liver,respiratory system,and adrenal glands.LC metastasis in the parotid gland is very rare,and its diagnosis presents a challenge.Here,we report a case of parotid metastasis in primary LC.CASE SUMMARY The patient was a 74-year-old male who was discovered to have bilateral facial asymmetry inadvertently two years ago.The right earlobe was slightly swollen and without pain or numbness.Computed tomography(CT)examination showed bilateral lung space-occupying lesions.Pulmonary biopsy was performed and revealed adenocarcinoma(right-upper-lung nodule tissue).Positron emission tomography-CT examination showed:(1)Two hypermetabolic nodules in the right upper lobe of the lung,enlarged hy-permetabolic lymph nodes in the right hilar and mediastinum,and malignant space-occupying lesion in the right upper lobe of the lung and possible metastasis to the right hilar and mediastinal lymph nodes;and(2)multiple hypermetabolic nodules in bilateral parotid glands.Parotid puncture biopsy was performed considering lung adenocarcinoma metastasis.Gene detection of lung biopsy specimens revealed an EGFR gene 21 exon L858R mutation.CONCLUSION This case report highlights the challenging diagnosis of parotid metastasis in LC given its rare nature.Such lesions should be differentiated from primary tumors of the parotid gland.Simple radiological imaging is unreliable,and puncture biopsy is needed for final diagnosis of this condition.

关 键 词：Lung cancer METASTASIS Parotid gland PATHOLOGY Positron emission tomography/computed tomography Case report 

分 类 号：R734.2[医药卫生—肿瘤]