Potential of molecular chaperones for treating Alzheimer’s disease  

作　　者：Gefei Chen Jan Johansson 

机构地区：[1]Department of Biosciences and Nutrition,Karolinska Institutet,Huddinge,Sweden [2]Department of Cell and Molecular Biology,Uppsala University,Uppsala,Sweden

出　　处：《Neural Regeneration Research》2024年第11期2343-2344,共2页中国神经再生研究（英文版）

基　　金：supported by grants from the Alzheimer’s Association Research Grant(to GC);Olle Engkvists Stiftelse(to GC);the Petrus and Augusta Hedlunds Stiftelse(to GC);Ake Wibergs stiftelse(to GC);the Swedish Alzheimer foundation(to GC);the Ahlén Stiftelsens(to GC);Karolinska Institutet Research Foundation Grant(to GC);the Stiftelsen for Gamla Tjanarinnor(to GC);the Stiftelsen Sigurd och Elsa Goljes Minne(to GC);the Loo and Hans Osterman Foundation(to GC);Geriatric Diseases Foundation at Karolinska Institutet(to GC);the Gun and Bertil Stohne’s Foundation(to GC);the Magnus Bergvall Foundation(to GC).

摘　　要：Alzheimer’s disease(AD)is the most prevalent form of dementia,i.e.,progressive memory loss and profound cognitive dysfunction,resulting in a considerable societal burden.At the neuropathological level,the brains of AD patients exhibit amyloid-β(Aβ)plaques,neurofibrillary tangles,and neuroinflammation(Sala Frigerio and De Strooper,2016).

关 键 词：ALZHEIMER INFLAMMATION AΒ 

分 类 号：R749.16[医药卫生—神经病学与精神病学]