圣乔治诺卡菌感染所致脊髓脓肿1例并文献复习  

Spinal cord abscess caused by Nocardia cyriacigeorgica:a case report and literature review

作　　者：王维荣 崔新宇 戴廷军[1] 姜政[2] 温冰[1] 徐广润[1] Wang Weirong;Cui Xinyu;Dai Tingjun;Jiang Zheng;Wen Bing;Xu Guangrun(Department of Neurology,Qilu Hospital,Shandong University,Jinan 250012,China;Department of Neurosurgery,Qilu Hospital,Shandong University,Jinan 250012,China)

机构地区：[1]山东大学齐鲁医院神经内科,济南250012 [2]山东大学齐鲁医院神经外科,济南250012

出　　处：《中华神经科杂志》2024年第2期179-184,共6页Chinese Journal of Neurology

摘　　要：报道1例圣乔治诺卡菌感染所致脊髓脓肿病例。患者为老年男性,有肾病综合征病史,主要表现为逐渐加重的腰痛、排尿困难、双下肢麻木无力。手术切除病灶后病理检查结果提示脊髓脓肿。脑脊液宏基因组二代测序确定圣乔治诺卡菌为致病病原体。尽管应用了抗生素治疗,患者还是在发病3个月后死亡。A case of spinal cord abscess caused by Nocardia cyriacigeorgica is reported.The patient is an elderly man with a history of nephritic syndrome who presented with aggravating lower back pain and then gradually developed urinary retention,weakness and numbness in both lower extremities.Operative intervention was performed,and postoperative pathological findings suggested spinal cord abscess formation.Metagenomic next-generation sequencing of the cerebrospinal fluid identified Nocardia cyriacigeorgica as the causative pathogen.Although appropriate antibiotics were prescribed,the patient died 3 months later.

关 键 词：脊髓脓肿 诺卡菌感染 肾病综合征 宏基因组二代测序 

分 类 号：R744[医药卫生—神经病学与精神病学]