柚皮素及其纳米递送体系研究进展  

Naringenin and its nano-delivery system:A review

作　　者：夏莎莎 王启明 饶哲楠 明建[1,2] XIA Shasha;WANG Qiming;RAO Zhenan;MING Jian(College of Food Science,Southwest University,Chongqing 400715,China;Research Center of Food Storage and Logistics,Southwest University,Chongqing 400715,China)

机构地区：[1]西南大学食品科学学院,重庆400715 [2]西南大学,食品贮藏与物流研究中心,重庆400715

出　　处：《食品与发酵工业》2024年第7期338-345,共8页Food and Fermentation Industries

基　　金：国家自然科学基金面上项目(32272308)。

摘　　要：柚皮素是广泛存在于柑橘类水果中一种黄酮类化合物,具有多种生理功效,如抗肿瘤、抗氧化和抗炎活性等。然而,由于柚皮素的疏水性,导致其生物利用度较差,应用潜力受到阻碍。为了提高柚皮素的生物利用度,研究人员开发了包括聚合物纳米颗粒、脂质体、纳米乳液、纳米混悬液在内的纳米递送系统。在此,该文对柚皮素的生理功能、体内代谢及其纳米递送体系进行了介绍,针对目前研究中存在的问题对未来柚皮素纳米递送体系的研究方向和应用前景进行了展望。Naringenin is a kind of flavonoid widely existing in citrus fruits,which has various physiological effects,such as anti-cancer,antioxidant,and anti-inflammatory activities.However,naringenin bioavailability is poor due to its hydrophobicity,which hinders its application potential.To improve the bioavailability of naringenin,researchers have developed nano-delivery systems including polymer nanoparticles,liposomes,nano-emulsions,and nano-suspensions.In this paper,the physiological function,metabolism,and nano-delivery system of naringenin were introduced.In view of the existing problems,the future research direction and application prospects of the naringenin nano-delivery system prospected.

关 键 词：柚皮素 生理功效 纳米递送体系 稳定性 生物利用度 

分 类 号：TS201.2[轻工技术与工程—食品科学]