基于文献计量分析益生菌微胶囊化研究现状及发展趋势  

A bibliometrics analysis of the current situation and development trend of probiotic microencapsulation research

作　　者：黄镇宇 徐磊[1] 孙培龙[1] 杨开[1] 蔡铭[1] 王舰 HUANG Zhenyu;XU Lei;SUN Peilong;YANG Kai;CAI Ming;WANG Jian(Department of Food Science and Technology,Zhejiang University of Technology,Hangzhou 310014,China)

机构地区：[1]浙江工业大学食品科学与工程学院,浙江杭州310014

出　　处：《食品与发酵工业》2024年第7期398-408,共11页Food and Fermentation Industries

基　　金：浙江省科技攻关计划项目(2023C02040,2022C02041);浙江省自然科学基金项目(LQ23C200013)。

摘　　要：益生菌产品对维护肠道健康的重要性不断被揭示,但无论是加工、贮藏、运输中的物理损伤还是摄入之后胃酸、胆汁盐等的胁迫,都会导致益生菌活力损失。为解决这些问题,利用微胶囊技术对益生菌进行包埋已经成为重要议题。该研究借助CiteSpace6.1.R6、VOSviewer1.6.19和Bibliometrix等文献计量工具,对1438篇中英文文献进行了分布特征分析。结果显示,益生菌微胶囊化研究正处于高速发展期,中国发文量领先,展现了未来发展的巨大潜力。包埋材料正在从壳聚糖与藻酸盐为主走向多元化发展,喷雾干燥技术取代冷冻干燥技术成为最常使用的微胶囊化手段。同时,各类生物活性材料的应用愈发频繁,多酚与人工酶将助力高自由度纳米封装。此外,益生菌与益生元的共封装或成为研究热点。结合关键词演变知识图谱,可以推测该领域未来研究热点,为研究者提供参考。The significance of probiotic products in maintaining intestinal health is continuously being unveiled.However,the physical damage during processing,storage,and transportation,as well as the stresses from gastric acid and bile salts after ingestion,can result in the loss of probiotic viability.To address these issues,the encapsulation of probiotics using microencapsulation technology has emerged as a crucial area of research.Bibliometric tools,including CiteSpace 6.1.R6,VOSviewer 1.6.19,and Bibliometrix were utilized to analyze a total of 1438 English and Chinese literature sources in this study.The results indicate that research on probiotic microencapsulation is experiencing rapid development,with China leading in the number of publications,showcasing significant potential for future advancements.Encapsulation materials have diversified beyond chitosan and alginate,and spray drying technology has emerged as the most studied method,surpassing freeze-drying.Moreover,the application of diverse bioactive materials,such as polyphenols and artificial enzymes,is becoming increasingly prevalent,enabling high-freedom nano-encapsulation.Additionally,co-encapsulation of probiotics and prebiotics is anticipated to be a prominent research focus.By integrating keyword evolution knowledge mapping,this study offers insights into future research hotspots in the field,thereby guiding researchers in their investigations.

关 键 词：益生菌 微胶囊化 文献计量 可视化 知识图谱 

分 类 号：G353.1[文化科学—情报学] TS201.3[轻工技术与工程—食品科学]