壳聚糖基营养递送体系的构建及其在食品中的应用研究进展  

Progress in Construction and Food Application of Chitosan-based Nutrient Delivery System

作　　者：刘蓬宇 王珂欣 周宇源 杨妍 邢竹青 高昂 LIU Pengyu;WANG Kexin;ZHOU Yuyuan;YANG Yan;XING Zhuqing;GAO Ang(College of Public Health and Health Sciences,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;College of Food Science and Engineering,Tianjin University of Science and Technology,Tianjin 300457,China;College of Food Science and Technology,Huazhong Agricultural University,Wuhan 430070,China)

机构地区：[1]天津中医药大学公共卫生与健康科学学院,天津301617 [2]天津科技大学食品科学与工程学院,天津300457 [3]华中农业大学食品科学技术学院,湖北武汉430070

出　　处：《食品工业科技》2024年第11期396-403,共8页Science and Technology of Food Industry

基　　金：国家自然科学基金(32202029);中医药重点学科建设项目-中医预防医学(2100601)。

摘　　要：壳聚糖是天然存在的碱性多糖,具有优异的生物相容性、生物可降解性、低毒性和易于制备等特点,已广泛应用于构建各类营养成分及生物活性物质的递送体系。壳聚糖基营养递送体系主要通过交联法、干燥法、层层自组装法、凝聚法、共价接枝法、微流控法及生物合成法等方法构建而成。壳聚糖可与碳水化合物、蛋白质及脂质体复配结合,形成的复合载体可获得更加优异的性能,拓宽其在食品包装材料、生物活性物质缓释以及益生菌包埋等方面的应用范围。此外,本文进一步分析了壳聚糖基营养递送体系在食品工业实际应用时的障碍与局限性,以期为壳聚糖基递送载体在赋予食品新的功能特性、开发新的食品配料以及营养素强化中的应用提供重要参考。Chitosan is a naturally-occurring alkaline polysaccharide with excellent biocompatibility,biodegradability,low toxicity,and easy preparation.It has been widely used in the construction of delivery systems for various nutrients and bioactive substances.The chitosan-based nutrient delivery systems are mainly constructed by cross-linking,drying,layer-by-layer self-assembly,coalescence,covalent grafting,microfluidics and biosynthesis.Chitosan can be combined with carbohydrates,proteins and liposomes to form a composite carrier that can obtain more excellent performance and broaden its application in food packaging materials,slow release of bioactive substances and probiotic embedding.In addition,this paper further analyzes the obstacles and limitations of the actual application of chitosan-based nutrient delivery systems in the food industry,to provide important references for the application of chitosan-based delivery carriers in imparting new functional properties to foods,developing new food ingredients,and nutrient fortification.

关 键 词：壳聚糖 递送体系 生物活性物质 缓释性能 载体构建 

分 类 号：TS201.1[轻工技术与工程—食品科学]