Antisense oligonucleotides provide optimism to the therapeutic landscape for tauopathies  

作　　者：Glenn A.Harris Lauren R.Hirschfeld 

机构地区：[1]Rainwater Charitable Foundation,Fort Worth,TX,USA

出　　处：《Neural Regeneration Research》2025年第3期803-804,共2页中国神经再生研究（英文版）

基　　金：supported by the Rainwater Charitable Foundation。

摘　　要：Tauopathies are a group of neurodegenerative diseases characterized by abnormal metabolism of the misfolded tau protein. Tau is encoded by the microtubule-associated protein tau gene(MAPT) and can be classified as either 3-repeat(3R) or 4-repeat(4R) based on the number of repeat domains from alternative splicing of exon 10 of the MAPT gene.

关 键 词：TAU METABOLISM DISEASES 

分 类 号：R741[医药卫生—神经病学与精神病学]