基于纳米酶生物传感器检测真菌毒素的研究进展  

Research Progress in the Detection of Mycotoxin Based on Nanoenzyme Biosensor

作　　者：张朱泽惠 李明 关桦楠 ZHANG Zhu-ze-hui;LI Ming;GUAN Hua-nan(School of Gain Science and Technology,Jiangsu University of Science and Technology,Zhenjiang 212100,China;College of Food Engineering,Harbin University of Commerce,Harbin 150076,China)

机构地区：[1]江苏科技大学粮食学院,江苏镇江212100 [2]哈尔滨商业大学食品工程学院,黑龙江哈尔滨150076

出　　处：《分析测试学报》2024年第6期945-954,共10页Journal of Instrumental Analysis

基　　金：国家自然科学基金项目(32372417);黑龙江省自然科学基金项目(LH2022C046);黑龙江省博士后科研启动项目(LBH-Q19027);黑龙江省领军人才支持计划(2020376);中央财政支持地方高校发展专项(YSL036)。

摘　　要：纳米酶作为一种具有天然模拟酶活性的纳米材料,因兼具纳米材料性能与类似天然酶的良好催化性能,已被广泛应用于新型真菌毒素生物传感器的研发。该文对纳米酶生物传感器检测原理进行了简单介绍,并根据真菌毒素检测机理进行分类,综述了近年比色、荧光和电化学纳米酶生物传感器在真菌毒素检测方面的研究进展,讨论并比较了上述3类纳米酶生物传感器在真菌毒素检测中的优势。最后,针对目前存在的问题和发展前景进行了展望。At present,nanoenzymes,as a kind of nanomaterials with natural mimic enzyme activi⁃ty,have been widely used to develop novel biosensors for the detection of fungal toxins because of the combination of nanomaterial properties and good catalytic properties similar to those of natural en⁃zymes.According to the signal transduction system of biosensors,there are three main types of nano⁃enzyme biosensors,namely,colorimetric,fluorescent and electrochemical methods.The applica⁃tions of nanoenzyme biosensors in mycotoxin detection in recent years are reviewed,and the advan⁃tages of the three types of nanoenzyme biosensors in mycotoxin detection is discussed.Finally,an outlook is given on the current problems and prospects for development.

关 键 词：食品分析 纳米酶 生物传感器 真菌毒素 食品安全 

分 类 号：O657.3[理学—分析化学] TS201.6[理学—化学]