Aquaporin-3 promotes proliferation and inflammation in hepatocellular carcinoma  

作　　者：Yao Wang Yalan Wu Xueying Li Weiwei Song Fengling Zheng Xiaoying Mo Yi Luo Yun Li Song Chen Huanhuan Luo 

机构地区：[1]School of Basic Medical Sciences,Guangzhou University of Chinese Medicine,Guangzhou,Guangdong 510006,China [2]The School of Health,Guangzhou Vocational University of Science andTechnology,Guangzhou,Guangdong 510555,China [3]Zhongshan Hospital of Traditional Chinese Medicine,Zhongshan,Guangdong 528401,China [4]The Journal Center,Guangzhou University of Chinese Medicine,Guangzhou,Guangdong 510006,China [5]Jiangsu Vocational College of Medicine,Yancheng,Jiangsu 224005,China [6]Science and Technology Innovation Center,Guangzhou University of Chinese Medicine,Guangzhou,Guangdong 510006,China [7]State Key Laboratory of Dampness Syndrome of Chinese Medicine,Guangzhou,Guangdong 510006,China

出　　处：《Genes & Diseases》2024年第4期45-48,共4页基因与疾病（英文）

基　　金：supported by grants from the National Natural Science Foundation of China(No.82174244,81973720);the Guangzhou Science and Technology Plan Project(Guangdong,China)(No.201904010185);the International Participant Application for Higher Education Track(China)(No.202110572025).

摘　　要：Carcinogenesis is closely associated with inflammation.Studies have shown that lipopolysaccharides(LPS)can contribute to hepatocellular carcinoma(HC)development by inducing IL-6 and TNF-αproduction from the hepatic progenitor cells.1 Aquaporin 3(AQP3),a water channel protein,has recently been found to play a critical role in cancer-associated inflammation.

关 键 词：inflammation. HEPATOCELLULAR INFLAMMATION 

分 类 号：R735.7[医药卫生—肿瘤]