Optimizing oncolytic virus design:a“Swiss army knife”approach to create a systemically delivered therapeutic  

作　　者：Carolina S.Ilkow John Cameron Bell 

机构地区：[1]Ottawa Hospital Research Institute,501 Smyth Road,Ottawa,ON,K1H 8L6,Canada

出　　处：《Signal Transduction and Targeted Therapy》2024年第5期1791-1792,共2页信号转导与靶向治疗（英文）

基　　金：C.S.I.and J.C.B.are supported by the Canadian Cancer Society Research Institute(CCSRI)and the Canadian Institutes of Health Research(CIHR).

摘　　要：In a recent paper published in Nature Biotechnology,Chen et al.1 describe a multiplex oncolytic virus platform that coupled with adoptive T cell therapy could solve the problem of repeat,systemic delivery of virus based therapeutics.It is widely accepted that multi-targeted therapeutic approaches attacking several facets of cancer biology are necessary to effectively deal with the tumor heterogeneity that exists within and between patients.

关 键 词：THERAPEUTIC al. TARGETED 

分 类 号：R730[医药卫生—肿瘤]