药食两用植物改善饮食诱导代谢性炎症研究进展  

Research progress of medicinal and edible plants in improving metabolic inflammation induced by diet

作　　者：徐沛沛 于静 羊金玲 孙喜贺 陈丽 XU Pei-Pei;YU Jing;YANG Jin-Ling;SUN Xi-He;CHEN Li(School of Public Health,Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China;Northwest Nutrition and Environment Related Diseases Prevention and Control Cooperative Innovation Center of Traditional Chinese Medicine,Lanzhou 730000,China)

机构地区：[1]甘肃中医药大学公共卫生学院,兰州730000 [2]西北营养与环境相关疾病中医药防控协同创新中心,兰州730000

出　　处：《食品安全质量检测学报》2024年第12期34-47,共14页Journal of Food Safety and Quality

基　　金：甘肃省中药原料质量监测技术服务中心建设基金资助项目(gszyzx201904);西北营养与环境相关疾病中医药防控协同创新中心2020年度开放基金项目(ZYXT-20-01)。

摘　　要：代谢性炎症具有缓慢性、隐匿性、持续性、关联性等特点,未加及时防治可能破坏机体稳态,导致代谢紊乱并且干扰能量平衡,继而引发肥胖、代谢综合征、代谢相关脂肪性肝病、动脉粥样硬化、2型糖尿病等难治病症。伴随着人类生活方式和饮食结构的改变,肥胖等慢性代谢性疾病已成为世界公共卫生健康备受关注的焦点,代谢性炎症作为这些疾病发病机制的启动因素,通过阻断其发生发展已成为代谢性疾病的重要防治策略。目前研究发现多种药食两用植物表现出良好的抗炎作用,其具有安全、稳定、易接受、毒副作用小及无耐药性等优势。本文通过从药食两用植物目录中筛选发挥缓解炎症、调节代谢等作用的植物及其有效成分,归纳总结改善饮食诱导代谢性疾病的相关作用机制,以期为深入研究代谢性疾病的预防和治疗提供参考。Metabolic inflammation is characterized by its slow,insidious,persistent,and interrelated nature.Without timely prevention and treatment,it may disrupt the homeostasis of the body,leading to metabolic disorders and interfering with energy balance.This can subsequently trigger obesity,metabolic syndrome,metabolic-related fatty liver disease,atherosclerosis,type 2 diabetes,and other difficult to treat conditions.With changes in human lifestyle and dietary structure,chronic metabolic diseases such as obesity have become a focus of global public health concern.As a trigger for the pathogenesis of these diseases,metabolic inflammation has become an important prevention and treatment strategy for metabolic diseases by blocking its occurrence and development.Current research has found that many medicinal and edible plants exhibit good anti-inflammatory effects,with advantages such as safety,stability,acceptability,low toxicity and side effects,and no drug resistance.This article aims to screen plants and their active ingredients from the directory of medicinal and edible plants that can alleviate inflammation and regulate metabolism.It summarized the relevant mechanisms of improving diet-induced metabolic diseases,providing a reference for further research on the prevention and treatment of metabolic diseases.

关 键 词：代谢性炎症 药食两用植物 有效成分 机制 

分 类 号：TS201.4[轻工技术与工程—食品科学]