Dietary selection of commensal protists:expanding host immunity by impacting trans-kindom competition with bacteria  

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作  者:Bo Li Min Wu Huaqiong Li 

机构地区:[1]Department of Neonatology,The Second Affliated Hospital of Wenzhou Medical University and Yuying Children’s Hospital,Wenzhou Medical University,Wenzhou,Zhejiang 325027,China [2]Zhejiang Engineering Research Center for Tissue Repair Materials,Wenzhou Institute,University of Chinese Academy of Sciences,Wenzhou,Zhejiang 325000,China

出  处:《Signal Transduction and Targeted Therapy》2024年第6期2344-2346,共3页信号转导与靶向治疗(英文)

基  金:funded by the startup grants from Wenzhou Institute,University of Chinese Academy of Sciences(WIUCASQD2019002,WIUCASQD2023029,WIUCAS2022020);the“Pioneer”and“Leading Goose”R&D Program of Zhejiang(2023C04043);National Key Research Project of MOST(SQ2023YFA1700082).

摘  要:In a recent publication in Cell,1 Elias R.Gerrick and colleagues identified novel commensal parabasalid protists(i.e.T.casperi,Parabasalia_sp_1653)with distinct metabolic traits,including diverse succinate excretion and dietary preference,which drives different trans-kingdom competition with specific commensal bacteria and results in divergent small intestine(SI)immune response,highlighting the significance of dietary interventions as a pivotal strategy for maintaining gut health(Fig.1).

关 键 词:IMMUNITY DIETARY INTESTINE 

分 类 号:R574[医药卫生—消化系统]

 

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