肠道菌群介导谷物阿魏酸代谢及其生理功效的研究进展  

Research Progress on Metabolism of Cereal Ferulic Acid Mediated by Gut Microbiota and Its Physiological Effects

作　　者：路士熠 程丹阳 安梦达 李洪岩 王静[1] LU Shiyi;CHENG Danyang;AN Mengda;LI Hongyan;WANG Jing(School of Food and Health,Beijing Technology and Business University,Beijing 100048,China)

机构地区：[1]北京工商大学食品与健康学院,北京100048

出　　处：《食品科学》2024年第18期307-314,共8页Food Science

基　　金：北京市教育委员会科技计划一般项目(KM202310011011);北京工商大学青年教师科研启动基金项目(QNJJ2022-13)。

摘　　要：阿魏酸是谷物中含量最丰富的酚酸,常以游离态和结合态两种形式广泛存在于谷物、豆类等植物基食品当中。阿魏酸具有抗氧化、抗炎、抗菌等多种功能活性,其在食品、医药方面具有较高的应用价值。尽管已有大量体内外实验结果表明谷物阿魏酸对维持肠道健康有重要意义,但对其肠道菌群代谢机制尚不明确。本文对近些年有关阿魏酸的肠道菌群代谢文献进行系统整理,从谷物阿魏酸的存在形式、其肠道释放与代谢及产生的生理健康效应3个方面详细总结了其进展情况,旨在为明确阿魏酸发挥肠道调控作用的分子机制提供新见解,为更好地开发利用谷物阿魏酸及其代谢物提供理论参考。Ferulic acid(FA),the most abundant phenolic acid in cereals,widely exists in both free and bound forms in grains,legumes and other plant-based foods.FA has various functional activities,such as antioxidant,anti-inflammatory and antibacterial properties,thus exhibiting high application values in the fields of food and medicine.To date,although a large number of in vivo and in vitro experiments have shown the importance of cereal FA in maintaining intestinal health,it is still unclear how FA is metabolized by the gut microbiota.In order to offer new insights into the molecular mechanism of the regulatory effect of FA the gut microbiota and offer a theoretical reference for better development and utilization of cereal FA and its metabolites,this paper provides a systematic review of the recent literature concerning intestinal microbial metabolism of cereal FA from three aspects of the existing forms,intestinal release and metabolism,and physiological health effects.

关 键 词：阿魏酸 存在形式 肠道代谢 代谢产物 健康功效 

分 类 号：TS201.2[轻工技术与工程—食品科学]