南瓜多糖结构特征、改善糖尿病作用的机制及影响因素研究进展  

Research Progress on the Structural Characteristics of Pumpkin Polysaccharide,Mechanism and Influencing Factors of Ameliorating Diabetes Mellitus

作　　者：韩亚楠 李晓娟[2] 王珣[2] 冷春旭[2] 赵曦[2] 赵伟[2] 陆杰[2] 李柱刚[3] HAN Yanan;LI Xiaojuan;WANG Xun;LENG Chunxu;ZHAO Xi;ZHAO Wei;LU Jie;LI Zhugang(Engineering Research Center of Agricultural Microbiology Technology,Ministry of Education&Heilongjiang Provincial Key Laboratory of Plant Genetic Engineering and Biological Fermentation Engineering for Cold Region&School of Life Sciences,Heilongjiang University,Harbin 150080,China;Biotechnology Research Institute,Heilongjiang Academy of Agricultural Sciences,Key Laboratory of Crop and Livestock Molecular Breeding of Heilongjiang,Engineering Technology Research Center of Pumpkin Breeding and Deep Processing of Heilongjiang,Harbin 150028,China;Institute of Tillage and Cultivation,Heilongjiang Academy of Agricultural Sciences,Harbin 150028,China)

机构地区：[1]黑龙江大学,生命科学学院,农业微生物技术教育部工程研究中心,黑龙江省寒区植物基因与生物发酵重点实验室,黑龙江哈尔滨150080 [2]黑龙江省农业科学院生物技术研究所,黑龙江省南瓜育种与深加工工程技术研究中心,黑龙江省作物与家畜分子育种重点实验室,黑龙江哈尔滨150028 [3]黑龙江省农业科学院耕作栽培研究所,黑龙江哈尔滨150028

出　　处：《食品工业科技》2024年第21期378-386,共9页Science and Technology of Food Industry

基　　金：黑龙江省省属科研院所科研业务费项目(CZKYF2021-2-B009);黑龙江省南瓜产业技术协同创新推广体系(岗位专家项目)。

摘　　要：多糖是南瓜中最主要的天然活性成分之一,结构易变、单糖成分复杂,具有降血糖、抗氧化等多种生物活性。近年来,随着糖尿病发病率上升,南瓜多糖的降糖功效引起学者们的关注,研究内容集中在多糖结构、单糖组分和不同活性作用机制等方面。本文对南瓜多糖的结构特征和改善糖尿病的主要作用机制进行了总结,归纳了南瓜多糖降糖活性影响因素,同时,对南瓜多糖药物活性研究的发展前景进行了展望并提出建议,以期为后续南瓜多糖对糖尿病的研究提供参考依据。Polysaccharides are one of the most important natural bioactive ingredients in pumpkin.Pumpkin polysaccharides have variable structure and complex monosaccharide composition,and possess a variety of biological activities such as hypoglycemia and antioxidant.In recent years,with the increasing incidence of diabetes,the hypoglycemic effect of pumpkin polysaccharides has attracted more and more attentions of scholars.The research focuses on the structure,monosaccharide composition and different mechanism of action of pumpkin polysaccharides.Therefore,this paper systematically summarizes the structural characteristics,mechanisms of hypoglycemic action and influence factors of hypoglycemic activity of pumpkin polysaccharides,and looks forward to its research direction and application prospects,and proposes the suggestions,with a view to providing reference for the subsequent research of pumpkin polysaccharides on diabetes.

关 键 词：南瓜多糖 糖尿病 结构特征 降糖机制 

分 类 号：TS201.4[轻工技术与工程—食品科学]