Impact of pre-existing cardiometabolic diseases on metastatic cancer stage at diagnosis:a prospective multinational cohort study  

作　　者：Anna Jansana Aviane Auguste Marina Kvaskoff Agnès Fournier Emma Fontvieille Laia Peruchet-Noray Carine Biessy Reynalda Cordova Kristina Elin Nielsen Petersen Anne Tjoneland Verena Katzke Rudolf Kaaks Fulvio Ricceri Salvatore Panico Paolo Contiero Maria-Jose Sánchez Jesus Castilla Marta Crous-Bou Alicia Heath Elom Kouassivi Aglago Elisabete Weiderpass Marc James Gunter Pietro Ferrari Elio Riboli Vivian Viallon Heinz Freisling 

机构地区：[1]International Agency for Research on Cancer(IARC-WHO),Lyon,France [2]Paris-Saclay University,University of Versailles-Saint-Quentin-en-Yveline,University Paris-Sud,French National Institute for Health and Medical Research(Inserm),Gustave Roussy,“Exposome and Heredity”Team,CESP,Villejuif,France [3]Department of Nutritional Sciences,University of Vienna,Vienna,Austria [4]Danish Cancer Society Research Center,Copenhagen,Denmark [5]Department of Public Health,University of Copenhagen,Copenhagen,Denmark [6]Division of Cancer Epidemiology,German Cancer Research Centre,Heidelberg,Germany [7]Department of Clinical and Biological Sciences,University of Turin,Turin,Italy [8]Unit of Epidemiology,Regional Health Service ASL TO3,Grugliasco,Turin,Italy [9]Department of Clinical Medicine and Surgery,Federico II University,Naples,Italy [10]Environmental Epidemiology Unit,Istituto di Ricovero e Cura a Carattere Scientifico(IRCCS)-Istituto Nazionale dei Tumori,Milan,Italy [11]Cancer Registry of Granada,Institute for Biosanitary Research of Granada(ibs.GRANADA),Granada,Spain [12]Epidemiology and Control of Chronic Diseases Group,Epidemiology and Public Health Networking Biomedical Research Centre,Madrid,Spain [13]Navarra Public Health Institute,Pamplona,Spain [14]Unit of Nutrition and Cancer,Cancer Epidemiology Research Program,Catalan Institute of Oncology(ICO)-Bellvitge Biomedical Research Institute(IDIBELL),L’Hospitalet de Llobregat,Barcelona,Spain [15]Department of Epidemiology,Harvard Tseng-Hsi Chan School of Public Health,Boston,Massachusetts,USA [16]Department of Epidemiology and Biostatistics,School of Public Health,Imperial College London,St Mary’s Campus,Norfolk Place,London,UK

出　　处：《Cancer Communications》2024年第5期593-597,共5页癌症通讯（英文）

基　　金：funded by the French National Cancer Institute(INCA_N◦2018-123)and supported by Canccrole Ile-de-France(N◦2018-1-PL SHS-06-CIRC-1);supported by the International Agency for Research on Cancer(IARC)and also by the Department of Epidemiology and Biostatistics,School of Public Health,Imperial College London,which has additional infrastructure support provided by the NIHR Imperial Biomedical Research Centre(BRC);supported by:Danish Cancer Society(Denmark);Ligue Contre le Cancer,Institut Gustave Roussy,Mutuelle Générale de l’Education Nationale,Institut National de la Santéet de la Recherche Médicale(INSERM)(France);German Cancer Aid,German Cancer Research Center(DKFZ),German Institute of Human Nutrition Potsdam-Rehbruecke(DIfE),Federal Ministry of Education and Research(BMBF)(Germany);Associazione Italiana per la Ricerca sul Cancro-AIRC-Italy,Compagnia di SanPaolo and National Research Council(Italy);Dutch Ministry of Public Health,Welfare and Sports(VWS),Netherlands Cancer Registry(NKR),LK Research Funds,Dutch Prevention Funds,Dutch ZON(Zorg Onderzoek Nederland),World Cancer Research Fund(WCRF),Statistics Netherlands(The Netherlands);Health Research Fund(FIS)-Instituto de Salud Carlos III(ISCIII),Regional Governments ofAndalucía,Asturias,Basque Country,Murcia and Navarra,and the Catalan Institute of Oncology-ICO(Spain);Swedish Cancer Society,Swedish Research Council and County Councils of Skane and Vasterbotten(Sweden);Cancer Research UK(14136 to EPIC-Norfolk;C8221/A29017 to EPIC-Oxford),Medical Research Council(1000143 to EPIC-Norfolk;MR/M012190/1 to EPIC-Oxford)(United Kingdom).

摘　　要：Owing to shared risk factors between cardiometabolic diseases(CMDs)and cancer,coupled with population aging,the lifetime risk of an individual developing cancer after a CMD is increasing.Furthermore,biological mechanisms such as insulin resistance or inflammation may not only predispose individuals withCMDto an elevated risk of certain types of cancer but also to a diagnosis of cancer at an advanced stage[1,2].

关 键 词：DIAGNOSIS DISEASES CANCER 

分 类 号：R73-37[医药卫生—肿瘤]