微针技术在食品安全检测领域的应用研究进展  

Research progress on the application of microneedle technology in the field of food safety detection

作　　者：曹书菡 宁雯秋 杨雨婷 展思敏 刘丽婷 邢佚男 贺美琳 孟凡达 CAO Shu-Han;NING Wen-Qiu;YANG Yu-Ting;ZHAN Si-Min;LIU Li-Ting;XING Yi-Nan;HE Mei-Lin;MENG Fan-Da(School of Clinical and Basic Medical Sciences,Shandong First Medical University&Shandong Academy of Medical Sciences,Ji’nan 250117,China;Yantai Key Laboratory of Nanomedicine&Advanced Preparations,Yantai Institute of Materia Medica,Yantai 264000,China)

机构地区：[1]山东第一医科大学临床与基础医学院,济南250117 [2]烟台市纳米药物与高端制剂重点实验室,烟台药物研究所,烟台264000

出　　处：《食品安全质量检测学报》2024年第22期173-180,共8页Journal of Food Safety and Quality

基　　金：山东省自然科学基金项目(ZR2022QB149);山东第一医科大学教育教学改革研究项目(XM2023016)。

摘　　要：随着生活水平的不断提高,人们的食品安全意识以及对食品安全的关注度逐渐增强。近年来,微针技术作为一种新兴的检测手段,在食品安全领域展现出了显著的应用潜力。微针技术利用微米级针状结构穿透食品表面,通过毛细作用采集内部液体样本,进而利用生物传感器对食品中的特定物质进行检测和分析。目前微针技术在食品中的食源性致病因子、致敏原、腐败程度、注水肉等方面的检测取得了显著成果。微针技术虽然在食品安全检测领域展现出巨大潜力,但依旧在提高微针的稳定性、优化采样机制以及扩展检测范围等方面面临着挑战。本文综述了微针技术在食品安全检测中的应用现状、技术优势及未来发展趋势。为微针技术在食品安全检测领域进一步发展提供参考。With the ongoing enhancement of living standards,there has been a gradual increase in public awareness and concern regarding food safety.In recent years,microneedle(MN)technology has emerged as an innovative detection method with significant potential applications in the realm of food safety.MN employs micron-scale needle-like structures to penetrate the surface of food items,facilitating the collection of internal liquid samples through capillary action,followed by analysis using biosensors to detect specific substances within the food matrix.Currently,MN technology has achieved significant achievements in the detection of foodborne pathogenic factors,allergens,spoilage levels,and water-added meat in food.MN technology,while demonstrating significant potential in the field of food safety testing,still faces challenges in enhancing the stability of microneedles,optimizing sampling mechanisms,and expanding the range of detection.This paper reviewed the current application status,technical advantages,and future developmental trends associated with MN technology in food safety detection.It provided reference for the further development of MN technology in the field of food safety detection.

关 键 词：微针技术 食品安全 检测技术 生物传感器 

分 类 号：TS207.3[轻工技术与工程—食品科学] TS201.6[轻工技术与工程—食品科学与工程]