磁性纳米材料的制备、修饰及其在真菌毒素检测和脱除中的应用研究进展  

Research Progress on the Preparation and Modification of Magnetic Nanomaterials and Their Application inMycotoxin Detection and Removal

作　　者：吕建欣 郭梦月 张会茹 孔丹丹 骆骄阳 杨美华 LÜJianxin;GUO Mengyue;ZHANG Huiru;KONG Dandan;LUO Jiaoyang;YANG Meihua(Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education,Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100193,China)

机构地区：[1]中国医学科学院·北京协和医学院药用植物研究所中草药物质基础与资源利用教育部重点实验室,北京100193

出　　处：《食品科学》2024年第24期357-366,共10页Food Science

基　　金：中国医学科学院医学与健康科技创新工程项目(2021-I2M-1-071);国家自然科学基金青年科学基金项目(82204618);上饶市“揭榜挂帅”企业重大技术需求榜单科技计划项目(2021A002)。

摘　　要：真菌毒素是产毒真菌天然产生的有毒小分子化合物。真菌毒素污染的产品一旦被人体摄入,极有可能产生致癌、致畸、致突变等不良影响。据报道,真菌毒素在食品与中药材中均有检出,开发有效方法对其进行快速检测以及绿色脱毒已成为研究重点。磁性纳米颗粒具有高比表面积、高表面能和高磁响应等特性,其作为磁性吸附剂载体在真菌毒素检测和脱除中有巨大的应用潜力。本文总结了常见磁性纳米材料的制备和功能化修饰方法及其在真菌毒素检测和脱除中的应用,并展望了其在真菌毒素控制中的未来发展趋势。Mycotoxins are toxic small-molecular-mass compounds produced naturally by toxigenic fungi.Ingestion of mycotoxin-contaminated products has a high potential to cause carcinogenic,teratogenic,and mutagenic effects in the human body.As mycotoxin residues have been detected in both foods and Chinese herbal medicine,the development of effective methods for rapid and highly sensitive detection as well as green detoxification of mycotoxins has become a research priority.Magnetic nanoparticles have high specific surface area,high surface energy and high magnetic response and hence have great potential for application as magnetic adsorbent carriers in mycotoxin detection and detoxification.This paper summarizes the methods used for the preparation and functionalized modification of common magnetic nanomaterials and their applications in mycotoxin detection and detoxification,and discusses future trends in mycotoxin control.

关 键 词：真菌毒素 磁性纳米材料 合成方法 检测 脱除 

分 类 号：TS207.3[轻工技术与工程—食品科学]