植物乳杆菌CCFM1280对小鼠运动性疲劳的缓解作用  

Alleviating effect of Lactobacillus plantarum CCFM1280 on exercise-induced fatigue in mice

作　　者：温欣 田培郡 严中汉 赵建新[1] 陈卫[1] 王刚[1] WEN Xin;TIAN Peijun;YAN Zhonghan;ZHAO Jianxin;CHEN Wei;WANG Gang(School of Food Science and Technology,Jiangnan University,Wuxi 214122,China)

机构地区：[1]江南大学食品学院,江苏无锡214122

出　　处：《食品与发酵工业》2024年第23期29-35,共7页Food and Fermentation Industries

基　　金：国家自然科学基金青年项目(32201988)。

摘　　要：肠道菌群已被证实能够影响宿主的健康和生理功能,并参与机体能量代谢和调节。近年来很多研究表明,调节肠道菌群可以有效提高运动表现。益生菌作为一种调节肠道菌群的微生态制剂,先前也被报道具有缓解疲劳、改善肌肉损伤等功效。该研究探讨了植物乳杆菌CCFM1280在改善运动耐力表现、减少疲劳代谢产物积累和增加能源物质储存方面的作用。结果表明,植物乳杆菌CCFF1280可显著增加小鼠力竭游泳时间,减少血清中血尿素氮和乳酸脱氢酶及肌肉中乳酸的含量,此外,CCFF1280还可显著提高肝糖原与肌糖原的含量,增加运动过程中能源储存。因此,植物乳杆菌CCFM1280具有缓解运动疲劳的潜力。The gut microbiota has been confirmed to affect the health and physiological functions of the host,and is involved in energy metabolism and regulation.Established research has proved that exercise capacity could be effectively promoted by the regulation of gut microbiota.Probiotics,as a type of microbial preparation that regulates the gut microbiota,have previously been reported to have effects such as alleviating fatigue and improving muscle damage.This study explored the role of Lactobacillus plantarum CCFM1280 in improving exercise endurance,reducing the accumulation of fatigue metabolites,and increasing energy storage.The results showed that CCFM1280 significantly increased the exhaustion swimming time of mice,reduced the levels of blood urea nitrogen and lactate dehydrogenase in serum,as well as the content of lactate in muscles.Additionally,CCFM1280 also significantly increased the content of liver glycogen and muscle glycogen,increasing energy storage during exercise.Therefore,Lactobacillus plantarum CCFM1280 has the potential to alleviate exercise fatigue.

关 键 词：植物乳杆菌 运动疲劳 肠道菌群 乳酸 肝糖原 肌糖原 

分 类 号：TS201.3[轻工技术与工程—食品科学]