乳清蛋白纳米载体递送生物活性物质研究进展  

Research Progress in the Whey Protein Nanocarriers Deliver Bioactive Components

作　　者：胡文梅 李慧雪 孙亚鹏 刘霄莹 张润峰 陈山[1] Hu Wenmei;Li Huixue;Sun Yapeng;Liu Xiaoying;Zhang Runfeng;Chen Shan(College of Light Industry and Food Engineering,Guangxi University,Nanning 530004)

机构地区：[1]广西大学轻工与食品工程学院,南宁530004

出　　处：《中国食品学报》2024年第11期424-437,共14页Journal of Chinese Institute Of Food Science and Technology

基　　金：国家自然科学基金地区科学基金项目(32260561)。

摘　　要：生物活性物质因在健康调节和疾病预防等方面表现出优异的功效而被研究者广泛关注,然而,其生物利用度低且易受环境条件影响,使应用范围受到限制。纳米递送体系已成为包埋生物活性物质和提高其生物利用度的有效途径之一。以乳清蛋白为基材的纳米载体体系具有出色功能特性,可以负载生物活性物质并实现控制释放,提高其生物利用度和稳定性,在众多纳米载体体系中脱颖而出。本文综述乳清蛋白的组成和功能特性,总结基于乳清蛋白的纳米递送体系类型,包括纳米乳液、多重乳液、乳液凝胶、自组装和纳米颗粒,同时概述相关递送体系的应用现状,并指出该研究领域存在的问题以及未来的研究方向,为后续研究提高乳清蛋白载体的稳定性和负载率,拓展其应用领域提供参考。Bioactive components are of great interest to researchers because of their excellent efficacy in health regulation and disease prevention.However,their bioavailability is low and easily affected by environmental conditions,limiting their application scope.The nano-delivery system has become one of the effective ways to embed bioactive components and improve their bioavailability.The nano-delivery system based on whey protein stands out among many nano-delivery systems because of its excellent functional characteristics,the advantages of loading bioactive components and achieving controlled release to improve their bioavailability and stability.This paper reviewed the composition and functional properties of whey protein,summarized the types of whey protein-based nano-delivery systems,including nano-emulsion,multi-emulsion,emulsion gels,self-assembly,and nanoparticles,and summarized the application status of these methods for delivering bioactive components.At the same time,the application status of relevant delivery systems was summarized,and the existing problems and future research directions in this research field were summarized,which provided a reference for subsequent research to improve the stability and loading rate of whey protein carriers and expand their application fields.

关 键 词：乳清蛋白 生物活性物质 递送体系 应用 

分 类 号：TS252.9[轻工技术与工程—农产品加工及贮藏工程]