Garcinia spp:Products and by-products with potential pharmacological application in cancer  

作　　者：Lavínia de C.Brito André Mesquita Marques Flávia da Cunha Camillo Maria Raquel Figueiredo 

机构地区：[1]Laboratório de Produtos Naturais (TecBio),Instituto de Tecnologia em Fármacos,FIOCRUZ,Rua Sizenando Nabuco,100,Rio de Janeiro,RJ,21041-250,Brazil

出　　处：《Food Bioscience》2022年第6期2138-2151,共14页食品生物科学（英文）

基　　金：the Farmanguinhos Institute of Technology in Pharmaceuticals/Oswaldo Cruz Foundation(FIOCRUZ).

摘　　要：The Garcinia genus belongs to the Clusiaceae family and is composed of approximately 240 species,distributed throughout the tropical regions,with a significant representation in Brazil.Their edible fruits have a high dietary value and have been recognized for their economic value as food and health.By-products of Garcinia fruits,such as the peel and seed of Garcinia brasiliensis,are a rich source of fibers,proteins,and bioactive metabolites,producing flour with an energetic value near wheat flour and antioxidant properties.Peel waste of G.mangostana(mangosteen)has been used as a green absorbent to recover valuable metals such as gold and silver from electronic waste.Many Garcinia species have obtained great prominence for extracts and isolated compounds,such as polyphenols,bioflavonoids,anthocyanins,benzophenones,and xanthones in the treatment of various illnesses.Thus,natural products isolated from Garcinia species have been described as having a chemical diversity and potential for medicinal uses with emphasizing adipogenesis,diabetes,cardiovascular illness,and cancer.This review comprises works published from January 2017 to March 2022 and highlights the promising anticancer activity and potential use of natural compounds from Garcinia species and fruit wastes.

关 键 词：CLUSIACEAE Anticarcinogenic ANTIPROLIFERATIVE CYTOTOXIC 

分 类 号：TS201[轻工技术与工程—食品科学] R285[轻工技术与工程—食品科学与工程]