supported by the National Natural Science Foundation of China(Nos.82273782 and U2004123);Training Program for Young Key Teachers of Colleges and Universities in Henan Province(No.2023GGJS008)。
In this work,we employed a ring-opening strategy to develop a series of novel N-benzyl arylamide derivatives as tubulin polymerization inhibitors.Notably,13n(MY-1388)exhibited remarkable antiproliferative potency on f...
supported by the National Natural Science Foundation of China(82274085);the Natural Science Foundation of Jiangsu Province(BK20220478);the Natural Science Foundation of Jiangsu Higher Education institutions of China(22KJB360010).
The anticancer potential of quassinoids has attracted a great deal of attention for decades,and scientific data revealing their possible applications in cancer management are continuously increasing in the literature....
Objective:To assess the effect of leaf extract of Persicaria lanigera on cotton pellet-induced granuloma tissue formation and acetic acid-induced ulcerative colitis.Methods:Rats were randomly divided into six groups:n...
supported by the National Natural Science Foundation of China (31671863);Young and Middle-aged Technological Innovation Talent Support Program of Shenyang Science and Technology Bureau (RC170247);Innovative Talent Support Program for Institution of Higher Learning of Liaoning Province (LR2017038)。
Abundant polyphenols make chokeberry have beneficial antioxidant and antiproliferative activity. In order to explore the contribution of different polyphenols in chokeberry to these activities, this study was conducte...
funded by Cyprus International University(Grant number:2019-03).
Propolis is a raw natural product produced by Apis mellifera for hive defence.Scientists have also investigated propolis in terms of different biological activities such as antimicrobial and anticancer effects for man...
the Farmanguinhos Institute of Technology in Pharmaceuticals/Oswaldo Cruz Foundation(FIOCRUZ).
The Garcinia genus belongs to the Clusiaceae family and is composed of approximately 240 species,distributed throughout the tropical regions,with a significant representation in Brazil.Their edible fruits have a high ...
supported by the National Natural Science Foundation of China(No.82173698);the Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme(2017);the Pearl River S&T Nova Program of Guangzhou(No.201806010169).
The rhizome of giant taro(Alocasia macrorrhiza(L.)Schott),which is a highly adaptable wild plant,is a traditional Chinese herbal medicine.In the current study,the antiproliferative constituents of giant taro were inve...
This study was conducted to assess the toxic effect of hydroethanolic extract combinations of Gnetum africanum Welv. leaves and Gnetum buchholzianum Engl. (Gnetaceae) in experimental rats to test the validity of the t...
Euphorbia maculata has long been used for managing different impairments in Asian countries.However,its antioxidant,anti-inflammatory and antiproliferative potentialities,along with its potential bioactive compounds r...
FJBB thanks Consejo Nacional de Ciencia y Tecnología,M´exico(CONACyT)for the scholarship(378371)granted.
Guava fruit is rich in phenolic compounds(PCs),whose metabolic fate has not been explored.Non-digestible carbohydrates and PCs in whole guava(WG)and seedless guava(SG)were submitted to an in vitro colonic fermentation...