New progress in roles of TGF-βsignaling crosstalks in cellular functions,immunity and diseases  

作　　者：Shuchen Gu Rik Derynck Ye-Guang Chen Xin-Hua Feng 

机构地区：[1]Center for Life Sciences,Shaoxing Institute,Zhejiang University,Shaoxing 321000,Zhejiang,China [2]The MOE Key Laboratory of Biosystems Homeostasis&Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology,Life Sciences Institute,Zhejiang University,Hangzhou 310058,Zhejiang,China [3]Cancer Center,Zhejiang University,Hangzhou 310058,Zhejiang,China [4]Department of Cell&Tissue Biology,University of California,San Francisco,CA 94143 San Francisco,USA [5]The MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors,Jiangxi Medical College,Nanchang University,Nanchang 330031,Jiangxi,China [6]The State Key Laboratory of Membrane Biology,Tsinghua‑Peking Center for Life Sciences,School of Life Sciences,Tsinghua University,Beijing,Beijing 100084,China [7]The Second Affiliated Hospital,Zhejiang University,Hangzhou,Zhejiang,China

出　　处：《Cell Regeneration》2024年第1期278-282,共5页细胞再生(英文)

基　　金：National Key Research and Development Program of China(2022YFC3401502 to X-H.F.,2023YFA1800603 to Y-G.C.);National Natural Science Foundation of China(U21A20356 and 32321002 to X-H.F.,31988101 to Y-G.C.);Zhejiang Provincial Natural Science Foundation(LD21C070001 to X-H.F.,LZ22C070001 to S.G.);Fundamental Research Funds for the Central Universities。

摘　　要：The family of secreted dimeric proteins known as the Transforming Growth Factor-β(TGF-β)family plays a critical role in facilitating intercellular communication within multicellular animals.A recent symposium on TGF-βBiology-Signaling,Development,and Diseases,held on December 19–21,2023,in Hangzhou,China,showcased some latest advances in our understanding TGF-βbiology and also served as an important forum for scientific collaboration and exchange of ideas.More than twenty presentations and discussions at the symposium delved into the intri-cate mechanisms of TGF-βsuperfamily signaling pathways,their roles in normal development and immunity,and the pathological conditions associated with pathway dysregulation.

关 键 词：TGF-βsuperfamily SIGNALING Development IMMUNITY DISEASES 

分 类 号：F42[经济管理—产业经济]