SIGNALING

作品数：1326被引量：6862H指数：32
导出分析报告
相关领域：医药卫生生物学更多>>
相关作者：刘琳郭静石茂华杨雅阁元少春更多>>
相关机构：浙江大学清华大学中山大学复旦大学更多>>
相关期刊：更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Extracellular vesicles:multiple signaling capabilities and translation into promising therapeutic targets to promote neuronal plasticity
《Neural Regeneration Research》2025年第12期3521-3522,共2页Dirk M.Hermann Bernd Giebel 
supported by the German Research Foundation(grants 514990328,389030878,405358801/428817542(within FOR2879)and 449437943(within TRR332,project C06);German Federal Ministry of Education and Science(3DOS,grant 161L0278B)(to DMH)。
Extracellular vesicles(EVs)are cell-derived,lipid membrane-enclosed vesicles carrying a broad spectrum of biologically active molecules(including proteins,RNAs,and bioactive lipids)which play important roles in interc...
关键词：PLASTICITY OXIDATIVE SPECTRUM 
Biochemical dissection of STAT3 signaling in amyotrophic lateral sclerosis
《Neural Regeneration Research》2025年第11期3229-3230,共2页Savina Apolloni Nadia D’Ambrosi 
funded by Fondazione AriSLA ETS(Fondazione di ricerca per la SLA ETS),ReNicALS project to SA;supported by#NEXTGENERATIONEU(NGEU)and funded by the Ministry of University and Research(MUR),National Recovery and Resilience Plan(NRRP),project MNESYS(PE0000006)-A Multiscale Integrated Approach to the Study of the Nervous System in Health and Disease(DN.1553 October 11,2022)。
Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disease characterized by the loss of upper and lower motor neurons,clinically marked by muscle atrophy and weakness.Although the clinical course is ...
关键词：STAT3 DISSECTION SCLEROSIS 
Understanding the link between type 2 diabetes mellitus and Parkinson's disease:role of brain insulin resistance
《Neural Regeneration Research》2025年第11期3113-3123,共11页Theodora Ntetsika Sergiu-Bogdan Catrina Ioanna Markaki 
support from Region Stockholm,ALF-project(FoUI-960041);Open Access funding is provided by Karolinska Institute(both to IM)。
Type 2 diabetes mellitus and Parkinson's disease are chronic diseases linked to a growing pandemic that affects older adults and causes significant socio-economic burden.Epidemiological data supporting a close relatio...
关键词：brain insulin resistance brain insulin signaling diabetes type 2 GLP-1 receptor agonists GLP-1 signaling insulin resistance insulin signaling NEURODEGENERATION Parkinson's disease targeted therapy 
Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function
《Neural Regeneration Research》2025年第10期2913-2914,共2页William J.Flerlage Mark L.Dell’Acqua Brian M.Cox Fereshteh S.Nugent 
supported by the National Institute of Mental Health (NIH/NIMH);the National Institute of Neurological Disorders and Stroke(NIH/NINDS):Grants#R21 MH132136 to FSN and R01 MH123700 and R01 NS040701 to MLD
There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(Simmons...
关键词：FUNCTION SUPPORTING 
Emerging potential of progranulin-dependent SorCS2 signaling in healthy and diseased nervous systems
《Neural Regeneration Research》2025年第9期2591-2593,共3页Alena Salasova Anders Nykjær 
supported by Danish National Research Foundation(#DNRF133)(to AN)。
The formation of the mammalian nervous system and its maturation into sensory,motor,cognitive,and behavioral circuits is a complex process that begins during early embryogenesis and lasts until young adulthood.Impaire...
关键词：progr jointly CS2 
Sotatercept:A novel therapeutic approach for pulmonary arterial hypertension through transforming growth factor-βsignaling modulation
《World Journal of Methodology》2025年第3期63-69,共7页Jyoti Bajpai Mehul Saxena Akshyaya Pradhan Surya Kant 
Pulmonary arterial hypertension(PAH)is a progressive disease marked by degeneration of the lung’s blood vessels.As the disease progresses,the resistance to blood flow in the pulmonary arteries increases,putting a str...
关键词：Pulmonary artery DRUGS Mean pulmonary artery pressure Transforming growth factor-βpathway PROTEIN 
Notch1 signaling regulates Sox9 and VEGFA expression and governs BMP2-induced endochondral ossification of mesenchymal stem cells
《Genes & Diseases》2025年第3期567-583,共17页Jing Zou Chengcheng Du Senrui Liu Piao Zhao Shengqiang Gao Bowen Chen Xiangdong Wu Wei Huang Zhenglin Zhu Junyi Liao 
supported by the Science and Technology Research Program of the Chongqing Education Commission(China)(No.KJQN202100431,KJZDM202100401);supported by the National Natural Science Foundation of China(No.81972069,82002312);CQMU Program for Youth Innovation in Future Medicine(Chongqing,China)(No.W0154);Innovation Project from Chongqing Municipal Education Commission(China)(No.CYB21169);Cultivating Program and Candidate of TipTop Talent of The First Affiliated Hospital of Chongqing Medical University(Chongqing,China)(No.BJRC2021-04);Cultivating Program of Postdoctoral Research of The First Affiliated Hospital of Chongqing Medical University(Chongqing,China)(No.CYYY-BSHPYXM-202202);Special Support from Chongqing Postdoctoral Research Program(Chongqing,China)(No.2021XM1029);upported by a postdoctoral fellowship from Chongqing Medical University and rewarded by China Postdoctoral Science Foundation(No.2022M720605).
Although bone morphogenetic protein 2 (BMP2) can induce chondrogenic differentiation of mesenchymal stem cells (MSCs), its induction of endochondral ossification limits theapplication of BMP2-based cartilage regenerat...
关键词：BMP2 Chondrogenic differentiation Endochondral ossification Mesenchymal stem cells Notch1 signaling 
Tnni3k regulates cardiomyopathy and cardiac conduction disease through Nfatc1 signaling
《Genes & Diseases》2025年第3期50-53,共4页Shi Ouyang Yujuan Niu Le Liu Qiaorong Yi Wuming Qin Hui Cao Tao Liao Rong Xiang Yonghe Ding Yun Deng 
supported in part by the National Natural Science Foundation of China(No.31970504,31772548,82371863,82070394);the NHC Key Laboratory of Birth Defect for Research and Prevention(Hunan Provincial Maternal and Child Health Care Hospital)(No.KF2021003);the Postgraduate Scientific Innovation Fund of Hunan Province,China(No.CX2018B302).
TNNI3K(troponin-I interacting kinase)encodes a duo tyrosine and serine/threonine kinase implicated in cardiomyopathy,arrhythmias,and cardiac conduction disease(CCD).1 However,no direct downstream phosphorylation targe...
关键词：generate splicing mutation splicing mutation zebrafish tnni k ortholog gene tnni k direct downstream phosphorylation targets cardiac conduction disease ccd CARDIOMYOPATHY nfatc signaling 
Cortical hem signaling center: functions, development, and potential implications for evolution and brain disorders
《Neural Regeneration Research》2025年第4期1079-1080,共2页Victor V.Chizhikov Igor Y.Iskusnykh 
supported by R01 NS093009 grant from NIH(to VVC).
Development of the telencephalon relies upon several signaling centers-localized cellular populations that supply secreted factors to pattern the cortical neuroepithelium.One such signaling center is the cortical hem,...
关键词：EPITHELIUM FIGURE CENTER 
Novel oral compound Z526 mitigates cancer-associated cachexia via intervening NF-κB signaling and oxidative stress
《Genes & Diseases》2025年第2期319-336,共18页Xiaofan Gu Shanshan Lu Shuang Xu Yiwei Li Meng Fan Guangyu Lin Yiyuan Liu Yun Zhao Weili Zhao Xuan Liu Xiaochun Dong Xiongwen Zhang 
supported by the National Natural Science Foundation of China (No.82373317,82374085,82303818,22377087);the Science and Technology Commission of Shanghai Municipality,China (No.20S11902200,16DZ2280100);the Natural Science Foundation of Shanghai Municipality,China (No.23ZR1460500);the China Postdoctoral Science Foundation (No.2023M731106)。
Cancer-associated cachexia(CAC)is a severe metabolic disorder syndrome mainly characterized by muscle and fat loss,which accounts for one-third of cancer-related deaths.No effective therapeutic approach that could ful...
关键词：Cancer-associated cachexia Fat lipolysis Muscle atrophy NF-κB signaling Oxidative stress Z526 
全选清除导出
共133页<12345678910>
检索报告 对象比较 聚类工具 使用帮助 返回顶部