Farnesol as a multifunctional candidate for treatment development  

作　　者：ANWAR ALI SREEKANTH REDDY OBIREDDY WING-FU LAI 

机构地区：[1]Department of Epidemiology and Health Statistics,Xiangya School of Public Health,Central South University,Changsha,410017,China [2]Department of Chemistry,Sri Krishnadevaraya University,Anantapur,515003,India [3]School of Food Science and Nutrition,University of Leeds,Leeds,LS29JT,UK

出　　处：《BIOCELL》2024年第2期163-171,共9页生物细胞(英文)

摘　　要：Farnesol is a C15 isoprenyl alcohol generated from the hydrolysis of farnesyl diphosphate under the action of farnesol synthase in plants.Although this sesquiterpenoid alcohol has been exploited in a wide variety of industrial applications,serious discussions on the possible use of this agent in disease treatment have been scant until now.In this article,we review the current understanding of the physiological properties of farnesol and the potential use of the agent as a candidate for treatment development.In fact,since the turn of the last century,farnesol has been found not only to trigger apoptosis in tumor cells but also to be able to function as a quorum-sensing molecule in Candida albicans to influence infection dynamics.By offering a snapshot of recent advances in research on farnesol,it is expected that this article can provide more insights into future research on farnesol for the development of different treatment strategies.

关 键 词：FARNESOL TREATMENT Natural products Health effects SIGNALING 

分 类 号：R37[医药卫生—病原生物学]