Farnesol is a C15 isoprenyl alcohol generated from the hydrolysis of farnesyl diphosphate under the action of farnesol synthase in plants.Although this sesquiterpenoid alcohol has been exploited in a wide variety of i...
the 2017 Wuhan Science and Technology Bureau Project(2017060201010222).
Objective:The purpose of this study is to explore the effect of Hirudin on the farnesoid X receptor(FXR)pathway during acute intrahepatic cholestasis in vivo and in vitro.Method:In vivo,sixty male Sprague-Dawley rats ...
This work was supported by the National Natural Science Foundation of China(31772176,31672038 and 31621064);and the National Key Research and Development Program of China(2017YFDO201900 and 2017YFD0200400).
Sesquiterpenoids play an import role in the direct or indirect defense of plants.Farnesyl pyrophosphate synthases(FPSs)catalyze the biosynthesis of farnesyl pyrophosphate,which is a key precursor of farnesol and(E)-β...
This work was supported by a grant from the National Natural Science Foundation of China(No.81571394).
Background:The phenotypic switching of Candida spp.plays an important role in the development of vulvovaginal candidiasis(VVC).Farnesol,as a quorum-sensing molecule in Candida albicans,has the ability to prevent yeast...
National Natural Sciences Foundation of China (Grant No.81271151 and Grant No.81371156);Jiangsu Qinglan Project Foundation(2012);The Foundation of the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD,2014-37)
Streptococcus mutans is a primary etiological agent of dental caries.Farnesol,as a potential antimicrobial agent,inhibits the development of S.mutans biofilm.In this study,we hypothesized that farnesol inhibits caries...