Epstein–Barr virus-associated gastric cancer:pathogenesis,molecular characterization,and emerging therapies  

作　　者：Yiqian Wang Dachuan Zhang Yue Zhang Meihua Wang Qing Li 

机构地区：[1]Department of Pathology,The Third Affiliated Hospital of Soochow University(Changzhou First People’s Hospital),Changzhou 213004,Jiangsu,China [2]Department of Pathology,Changzhou Cancer Hospital,Changzhou 213032,Jiangsu,China

出　　处：《感染控制(英文)》2024年第4期23-32,共10页

基　　金：Research on the key technology of injectable hydrogel drug delivery system and its application in tumor therapy(CJ20245007).

摘　　要：Gastric cancer is the fifth most common malignant tumor in the world in terms of morbidity and mortality,with a high prevalence of gastric cancer in Asia,especially in China,Japan,and South Korea.Gastric cancer is strongly associated with Epstein-Barr virus,and gastric cancer cases positive for Epstein-Barr virus are referred to as Epstein-Barr virus-associated gastric cancer(EBVaGC).EBVaGC has unique clinicopathological features and molecular characteristics,and the study of EBVaGC provides new perspectives for the early diagnosis and personalized treatment of gastric cancer.Here,we present a review of the research progress in the epidemiology,pathogenesis,clinicopathologic features and prognosis,molecular features,diagnosis,and treatment of EBVaGC.

关 键 词：EBV EBVaGC PATHOGENESIS IMMUNOTHERAPY 

分 类 号：R73[医药卫生—肿瘤]