营养素在年龄相关性黄斑变性中的最新研究进展  

Recent advances in nutrients in age-related macular degeneration

作　　者：王昌琴 吕洋 WANG Changqin;LV Yang(Ophthalmology Center of the 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army,Lanzhou 730000,Gansu Province,China;The First Clinical Medical College of Gansu University of Traditional Chinese Medicine,Lanzhou 730000,Gansu Province,China)

机构地区：[1]中国人民解放军联勤保障部队第九四○医院眼科中心,甘肃省兰州市730000 [2]甘肃中医药大学第一临床医学院,甘肃省兰州市730000

出　　处：《眼科新进展》2025年第5期410-415,共6页Recent Advances in Ophthalmology

基　　金：甘肃省卫生健康委员基金资助项目(编号:GSWSKY2022-05);甘肃省自然科学基金项目(编号:24JRRA003);军队课题(编号:2024-G2-4);兰州市科技计划项目(编号:2024-9-126)。

摘　　要：年龄相关性黄斑变性(AMD)是导致中老年人群视力损害和失明最主要的原因之一,主要表现为中心视力逐渐丧失,严重影响患者的日常生活及生活质量。尽管近年来医学技术不断进步,但对AMD的发病机理和有效治疗方法仍存在诸多未解之谜。目前,AMD的发病机制尚不完全清楚,但已被证实与遗传因素、环境因素和生活方式等相关。近年来,越来越多的研究表明,饮食因素,尤其是营养素,在AMD的发生发展中起着重要作用。本文将综合分析现有研究成果,探讨营养素在AMD发病机制中的具体影响,为预防和治疗AMD提供科学依据。Age-related macular degeneration(AMD)is one of the leading causes of visual impairment and blindness in middle-aged and elderly people.The main manifestation of AMD is the gradual loss of the central vision,which seriously affects the daily life and quality of life of patients.Despite recent advances in medical technology,there are still many mysteries about the pathogenesis and effective treatment of AMD.Although the pathogenesis of AMD has not been fully understood,it has been confirmed to be related to multiple factors such as genetic factors,environmental factors,and lifestyle.In recent years,more and more studies have shown that dietary factors,especially nutrients,play an important role in the occurrence and development of AMD.This review will comprehensively analyze the existing research results and explore the specific effects of nutrients in the pathogenesis of AMD,thus providing a scientific foundation for the prevention and treatment of this disease.

关 键 词：年龄相关性黄斑变性 营养素 碳水化合物 蛋白质 脂肪 维生素 矿物质 

分 类 号：R774.1[医药卫生—眼科]