高分辨气相色谱/双聚焦磁式质谱联用仪(HRGC/HRMS)检测奶粉中二噁英  

Determination of 2,3,7,8- Chlorine - Substiturted Dibenzo - p - dioxins and furans in milk pouder by Isotope Dilution High Resolution Gas Chromatography/High Resolution Mass Spectrometry(HRGC/HRMS)

作　　者：姜杰[1] 张建清[1] 周健[1] 刘桂华[1] 

机构地区：[1]深圳市疾病控制中心,广东518020

出　　处：《中国卫生检验杂志》2002年第5期530-532,共3页Chinese Journal of Health Laboratory Technology

摘　　要：[目的]采用高分辨气相色谱/高分辨双聚焦磁式质谱联用仪（HRGC/HRMS）定量检测了奶粉中十七个四至八个氯原子取代的二（口恶）英和呋哺。[方法]采用美国EPA1613方法进行严格的质量控制和同位素稀释的方法定量,对奶粉样品进行索式抽提、自动纯化系统纯化、以HRGC/HRMS-MID方法检测样品中的二（口恶）英。[结果]同位素标准物的回收率分布于90.6％～116.28％之间,检出限在0.077-0.97pg/g。该方法定量可精确到pg/g水平。实验过程中可以控制系统不受污染,样品中只检出1,2,3,4,7,8-HxCDF。[结论]该方法灵敏、定性、定量准确,为目前国际上权威认可的二（口恶）英定量检测方法。[Objective]2,3,7,8 - Chlorine - Substituted Dibenzo - dioxins and furans in milk pouder were determined by High -resolution Gas Chromatography/High - resolution Mass Spectrometry. [Methods] Dibenzo - p - Dioxins and Dibenzo - Furans were extracted from milk pouder by Soxhlet extraction,FMS cleaning up and HRGC/HRMS- MID determination and quantitation in pg/g level, using isotope dilution methodology. [Results]The result showed that the system was not contaminated.The recovery was 90.64% - 116. 28% ,the detections limit was low(0.077 - 0.97pg/g).Only 1,2,3,4,7,8- HxCDF was detected in the experiment. [Conclusions]The method is sensitive,accurate.

关 键 词：高分辨气相色谱/高分辨双聚焦磁式质谱联用仪 同位素稀释 二恶英 奶粉 质量检测 

分 类 号：R155.57[医药卫生—营养与食品卫生学] TS25[医药卫生—公共卫生与预防医学]