十二碳二元酸发酵研究  

Study on Fermentation of 1,12-Dodecanedioic Acid

作　　者：刘树臣[1] 李淑兰[1] 金平[1] 方向晨[1] 

机构地区：[1]抚顺石油化工研究院,抚顺113001

出　　处：《微生物学报》2002年第6期748-750,共3页Acta Microbiologica Sinica

摘　　要：The effects of fermentative conditions such as control mode of pH,concentration of cells and dissolved oxygen on fermentation of 1,12-dodecanedioic acid from n-dodecane by a mutant,Candida tropicalis SP-UV-56,were studied.Suitable concentration of cells is 15g/L～17g/L,dissolved oxygen level is preferably kept at 20%～30%.The control mode of pH by gradually going up adjusted with NaOH solution was suggested while pH range is 7.4～8.4.Under the optimal conditions the DCA12 yield of 166g/L was obtained after 144h cultivation.This shows that the mutant is a high-yield strain for 1,12-dodecanedioic acid production.The effects of fermentative conditions such as control mode of pH,concentration of cells and dissolved oxygen on fermentation of 1,12-dodecanedioic acid from n-dodecane by a mutant,Candida tropicalis SP-UV-56,were studied.Suitable concentration of cells is 15g/L～17g/L,dissolved oxygen level is preferably kept at 20%～30%.The control mode of pH by gradually going up adjusted with NaOH solution was suggested while pH range is 7.4～8.4.Under the optimal conditions the DCA12 yield of 166g/L was obtained after 144h cultivation.This shows that the mutant is a high-yield strain for 1,12-dodecanedioic acid production.

关 键 词：十二碳二元酸 发酵 长链二元酸 热带假丝酵母 

分 类 号：TQ920[轻工技术与工程—发酵工程]