43例智力低下和发育异常患者的细胞遗传学分析  

Cytogenetics Karyotype Analysis in the Patients with Lower lntelligence and physically

作　　者：马志敏[1] 张励[1] 陈玲[1] 阿周存[1] 

机构地区：[1]大理学院生化分子生物学教研室,云南大理671000

出　　处：《大理学院学报（医学版）》2002年第2期16-17,27,共3页

摘　　要：目的 :探讨智力低下和发育异常的遗传学原因。方法 :对43例智力低下和发育异常的患者进行外周血染色体分析。结果 :发现异常染色体核型14例 ,异常检出率为32 56%。结论 :结果表明染色体异常是导致智力低下和发育异常的重要原因。objective:To study the genetic causes of lower intelligence and physically maldevelopment.Methods:43 subjects who were intelligence and physically maldevelopment were selected for cytogenetics karyotype analysis.Results:The incidence of chromosome aberration was 32.56%(14/43).Conclusions:Chromosome aberration is important causes of lower intelligence and physically maldeveioped.

关 键 词：智力低下 发育异常 细胞遗传学 染色体异常 外周血 

分 类 号：R749.93[医药卫生—神经病学与精神病学] Q343[医药卫生—临床医学]