茵陈蒿对黄曲霉毒素B_1诱发的遗传损伤的影响  

The Impact of Artemisia Scopariae on Hereditary Injury Induced by Aflatoxin B_1

作　　者：洪振丰[1] 叶挺兴 陈少华[2] 刘凌冰[3] 林丽[3] 

机构地区：[1]福建中医学院,福建福州市五四北路53号350003 [2]空军福州医院 [3]福建医学院

出　　处：《中医杂志》1992年第8期44-45,共2页Journal of Traditional Chinese Medicine

摘　　要：黄曲霉毒素B_1(AFB_1)诱发的小鼠骨髓细胞微核(MN)千分率随茵陈蒿剂量的增加而呈下降趋势,茵陈蒿对AFB_1诱发的染色体畸变(CA)百分率和姐妹染色单体交换数(SCE)/细胞的抑制作用呈量效关系。It was observed that the per mil rate of micronuclei of marrow cells in mice induced by AFB_1 decreased with the increasing dosage of Artemisia Scopariae. While A. Scopariae revealed dosage-effect relation in the percentage of CA(chromatin abnomalities)induced by AFB_1 and the inhibition effect on SCE(sister chromatin exchange)per cell.

关 键 词：茵陈 染色体畸变 黄曲霉毒素 

分 类 号：R730.1[医药卫生—肿瘤]