A Review of Immune System Components, Cytokines, and Immunostimulants in Cultured Finfish Species  

作　　者：Timothy J. Bruce Michael L. Brown 

机构地区：[1]Missouri Department of Conservation, Lost Valley Hatchery, Warsaw, Missouri, USA [2]Department of Natural Resource Management, South Dakota State University, Brookings, South Dakota, USA

出　　处：《Open Journal of Animal Sciences》2017年第3期267-288,共22页动物科学期刊（英文）

摘　　要：Aquaculture is a rapidly growing global agriculture sector and the importance of fish health has become of upmost importance as production levels and stocking densities increase. Over the past few decades, there have been a large number of immunological investigations on commonly cultured finfish species. Further, new technologies and strategies that embody use of fish immunostimulants, probiotics, and vaccinology rely heavily upon a comprehensive understanding of teleost immune system mechanics. The teleost immune system works in concert to properly recognize, control, and clear aquatic pathogens. Recent findings have exemplified the cooperative efforts of the nonspecific and adaptive branches, and have put forth an emphasis on the importance of the mucosal immune response in all aspects of a mounted immune response. This review provides a generalized overview of the innate and adaptive arms of the fish immune system, and provides highlights of recently published work in the areas of signaling networks and mucosal immune interactions.Aquaculture is a rapidly growing global agriculture sector and the importance of fish health has become of upmost importance as production levels and stocking densities increase. Over the past few decades, there have been a large number of immunological investigations on commonly cultured finfish species. Further, new technologies and strategies that embody use of fish immunostimulants, probiotics, and vaccinology rely heavily upon a comprehensive understanding of teleost immune system mechanics. The teleost immune system works in concert to properly recognize, control, and clear aquatic pathogens. Recent findings have exemplified the cooperative efforts of the nonspecific and adaptive branches, and have put forth an emphasis on the importance of the mucosal immune response in all aspects of a mounted immune response. This review provides a generalized overview of the innate and adaptive arms of the fish immune system, and provides highlights of recently published work in the areas of signaling networks and mucosal immune interactions.

关 键 词：INNATE IMMUNITY Adaptive IMMUNITY CYTOKINES IMMUNOSTIMULATION AQUACULTURE 

分 类 号：R73[医药卫生—肿瘤]