New Hemisynthetic Oleanane Saponin with Antimicrobial Activities  

作　　者：Cyrille Ngoufack Tagousop Jean-De-Dieu Tamokou Leonel Donald Tsamo Feugap Dominique Harakat Laurence Voutquenne-Nazabadioko David Ngnokam Cyrille Ngoufack Tagousop;Jean-De-Dieu Tamokou;Leonel Donald Tsamo Feugap;Dominique Harakat;Laurence Voutquenne-Nazabadioko;David Ngnokam(Department of Basic Scientific Studies, University Institute of Technology, University of Ngaoundere, Ngaoundere, Cameroon;Research Unit of Environmental and Applied Chemistry, Department of Chemistry, Faculty of Science, University of Dschang, Dschang, Cameroon;Research Unit of Microbiology and Antimicrobial Substances, Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon;Service Commun d’Analyses, Institut de Chimie Moléculaire de Reims (ICMR), CNRS UMR 7312, Reims, France;Groupe Isolement et Structure, Institut de Chimie Moléculaire de Reims (ICMR), CNRS UMR 7312, Reims, France)

机构地区：[1]Department of Basic Scientific Studies, University Institute of Technology, University of Ngaoundere, Ngaoundere, Cameroon [2]Research Unit of Environmental and Applied Chemistry, Department of Chemistry, Faculty of Science, University of Dschang, Dschang, Cameroon [3]Research Unit of Microbiology and Antimicrobial Substances, Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon [4]Service Commun d’Analyses, Institut de Chimie Moléculaire de Reims (ICMR), CNRS UMR 7312, Reims, France [5]Groupe Isolement et Structure, Institut de Chimie Moléculaire de Reims (ICMR), CNRS UMR 7312, Reims, France

出　　处：《Advances in Biological Chemistry》2021年第1期1-11,共11页生物化学进展（英文）

摘　　要：<span style="font-family:Verdana;">A new hemisynthetic oleanane saponin: </span><span><span><span style="font-family:""><span style="font-family:Verdana;">4',2",3",4",6"-penta-</span><i><span style="font-family:Verdana;">O</span></i><span style="font-family:Verdana;">-acetyl-6'-</span><i><span style="font-family:Verdana;">O</span></i><span style="font-family:Verdana;">-</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">methyl-3-</span><i><span style="font-family:Verdana;">O</span></i><span style="font-family:Verdana;">-</span><i><span style="font-family:Verdana;">β</span></i><span style="font-family:Verdana;">-D-glucopyranosyl-(1→2)-</span><i><span style="font-family:Verdana;">β</span></i><span style="font-family:Verdana;">-D-glucuronopyranosyl oleanolic acid (</span><b><span style="font-family:Verdana;">2</span></b><span style="font-family:Verdana;">)</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> was obtain</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">ed</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> after acetylation and methylation reaction on </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">3-</span><i><span style="font-family:Verdana;">O</span></i><span style="font-family:Verdana;">-</span><i><span style="font-family:Verdana;">β</span></i><span style="font-family:Verdana;">-D-</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">glucopyranosyl-(1→2)-</span><i><span style="font-family:Verdana;">β</span></i><span style="font-family:Verdana;">-D-glucuronopyranosyl oleanolic acid (</span><b><span<span style="font-family:Verdana;">A new hemisynthetic oleanane saponin: </span><span><span><span style="font-family:""><span style="font-family:Verdana;">4',2",3",4",6"-penta-</span><i><span style="font-family:Verdana;">O</span></i><span style="font-family:Verdana;">-acetyl-6'-</span><i><span style="font-family:Verdana;">O</span></i><span style="font-family:Verdana;">-</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">methyl-3-</span><i><span style="font-family:Verdana;">O</span></i><span style="font-family:Verdana;">-</span><i><span style="font-family:Verdana;">β</span></i><span style="font-family:Verdana;">-D-glucopyranosyl-(1→2)-</span><i><span style="font-family:Verdana;">β</span></i><span style="font-family:Verdana;">-D-glucuronopyranosyl oleanolic acid (</span><b><span style="font-family:Verdana;">2</span></b><span style="font-family:Verdana;">)</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> was obtain</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">ed</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> after acetylation and methylation reaction on </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">3-</span><i><span style="font-family:Verdana;">O</span></i><span style="font-family:Verdana;">-</span><i><span style="font-family:Verdana;">β</span></i><span style="font-family:Verdana;">-D-</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">glucopyranosyl-(1→2)-</span><i><span style="font-family:Verdana;">β</span></i><span style="font-family:Verdana;">-D-glucuronopyranosyl oleanolic acid (</span><b><span

关 键 词：SAPONIN ACETYLATION METHYLATION Antimicrobial Activities 

分 类 号：O17[理学—数学]