云南高校图书馆联盟文献共享服务平台- ACETYLATION

ACETYLATION: 作品数：221被引量：584H指数：10; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：孙树汉杨富秦樾刘永军何凤田更多>>; 相关机构：中国科学院上海生命科学研究院第二军医大学清华大学华中科技大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>

Enhanced autophagic clearance of amyloid-βvia histone deacetylase 6-mediated V-ATPase assembly and lysosomal acidification protects against Alzheimer's disease in vitro and in vivo: 《Neural Regeneration Research》2025年第9期2633-2644,共12页Zhimin Long Chuanhua Ge Yueyang Zhao Yuanjie Liu Qinghua Zeng Qing Tang Zhifang Dong Guiqiong He; supported by the National Natural Science Foundation of China,No.82201582(to QT);Scientific and Technological Research Program of Chongqing Municipal Education Commission,No.KJQN202200457(to QT);General Project of Changqing Natural Science Foundation,No.cstc2021jcyjmsxmX0442(to ZL);CQMU Program for Youth Innovation in Future Medicine,No.W0044(to ZD and GH);Direct Research Project for PhD of Chongqing,No.CSTB2022BSXM-JCX0051(to ZL);the Project of the Top-Notch Talent Cultivation Program For the Graduate Students of Chongqing Medical University,No.BJRC202310(to CG)。; Recent studies have suggested that abnormal acidification of lysosomes induces autophagic accumulation of amyloid-βin neurons,which is a key step in senile plaque formation.Therefore,resto ring normal lysosomal funct...; 关键词：Alzheimer's disease amyloid-β APP/PS1 mice autophagy cognitive impairment histone deacetylase 6 lysosomal acidification microtubule acetylation valproic acid V-ATPASE

Improving regulatory T cell-based therapy:insights into post-translational modification regulation: 《Journal of Genetics and Genomics》2025年第2期145-156,共12页Aiting Wang Yanwen Wang Rui Liang Bin Li Fan Pan; supported by grants from the National Key R&D Program of China(2022YFC2403000 and 2021YFC2400500);the National Natural Science Foundation of China(32200728 and 32170925);the Clinical Research Project of Shenzhen Medical Academy of Research and Translation(C2301008);Shenzhen Science and Technology Program(JCYJ20220531100406014,JCYJ2022081800807016,RCBS20221008093336088,KQTD20210811090115019);Guangdong Basic and Applied Basic Research Foundation(2021A1515110375);the Innovative Research Team of High-level Local Universities in Shanghai(SHSMU-ZDCX20210601).; Regulatory T(Treg)cells are pivotal for maintaining immune homeostasis and play essential roles in various diseases,such as autoimmune diseases,graft-versus-host disease(GVHD),tumors,and infectious diseases.Treg cells...; 关键词：Treg cell FOXP3 UBIQUITINATION ACETYLATION PHOSPHORYLATION METHYLATION GLYCOSYLATION Post-translational modification

Microwave-Assisted Acetylated Lignin Loaded into Cellulose Acetate for Efficient UV-Shielding Films: 《Journal of Renewable Materials》2025年第2期401-412,共12页Ahmed M.Khalil Samir Kamel; Developing favorable bio-based polymers that replace petroleum-based plastics is an essential environmental demand.Lignin is a by-product of the chemical pulping industry.It is a natural UV protection ingredient in br...; 关键词：Cellulose acetate microwave-assisted acetylation nano lignin acetate UV-SHIELDING

PDHX acetylation facilitates tumor progression by disrupting PDC assembly and activating lactylation-mediated gene expression: 《Protein & Cell》2025年第1期49-63,共15页Zetan Jiang Nanchi Xiong Ronghui Yan Shi-ting Li Haiying Liu Qiankun Mao Yuchen Sun Shengqi Shen Ling Ye Ping Gao Pinggen Zhang Weidong Jia Huafeng Zhang; supported in part by National Natural Science Foundation of China(Grant Nos.81930083,82192893,81821001,and 82303217);National Key R&D Program of China(2022YFA1304504);the Chinese Academy of Sciences(XDB39000000);the Global Select Project(DJK-LX-2022001)of the Institute of Health and Medicine,Hefei Comprehensive National Science Center;the Fundamental Research Funds for the Central Universities(WK9100000051).; Deactivation of the mitochondrial pyruvate dehydrogenase complex(PDC)is important for the metabolic switching of cancer cell from oxidative phosphorylation to aerobic glycolysis.Studies examining PDC activity regulati...; 关键词：ACETYLATION lactylation liver cancer PDC PDHX

Improving the performance of paper-based separator for lithium-ion batteries application by cellulose fiber acetylation and metal-organic framework coating: 《Frontiers of Chemical Science and Engineering》2024年第12期33-42,共10页Wei Wang Xiangli Long Liping Pang Dawei Shen Qing Wang; This work was supported by the Basic Ability Improvement Project for Young Teachers in Guangxi Colleges and Universities(Grant No.2023KY0396);Doctoral Research Start-up Fund of Nanning Normal University(Grant No.602021239438);the Scientific and Technological Project of Henan Province(Grant No.232102230071);the Key Scientific Research Projects of Henan Higher Education Institutions(Grant No.23B550006);Foundation of Central Laboratory of Xinyang Agriculture and Forestry University(Grant No.FCL202110).; Paper-based separator for lithium-ion battery application has attracted great attention due to its good electrolyte affinity and thermal stability.To avoid the short circuit by the micron-sized pores of paper and impr...; 关键词：paper-based separators lithium-ion batteries ACETYLATION metal-organic framework coating

PCAF-mediated acetylation of METTL3 impairs mRNA translation efficiency in response to oxidative stress: 《Science China(Life Sciences)》2024年第10期2157-2168,共12页Cheng Liu Miao Yu Mengyuan Wang Siyuan Yang Yenan Fu Lei Zhang Chaoyang Zhu Hongquan Zhang; supported by the National Key Research and Development Program of China(2022YFA1104003,2021YFC2501003);the National Natural Science Foundation of China(82230094,81972616,81730071);Peking University Medicine Sailing Program for Young Scholars'Scientific&Technological Innovation(BMU2024YFJHPY004);the Fundamental Research Funds for the Central Universities。; METTL3 methylates RNA and regulates the fate of mRNA through its methyltransferase activity.METTL3 enhances RNA translation independently of its catalytic activity.However,the underlying mechanism is still elusive.Her...; 关键词：METTL3 ACETYLATION PCAF m^(6)A oxidative stress TRANSLATION SIRT3

TaSRT2 recognizes a viral protein to activate host immunity byincreasing histone acetylation: 《Science Bulletin》2024年第20期3206-3211,共6页Kaili Zhong Yaoyao Jiang Haichao Hu Bowen Yuan Mila Wu Aizhu Tu Gecheng Xu Linna Cai Tingting Liu Shiqi Gao Linzhi Li Qiansheng Liao Lidan Guo Ye Xia Peng Liu Ye Cheng Lin Lin Chuanxi Zhang Jianping Chen Jian Yang; supported by the National Key Research and Development Program of China(2023YFD1400300);Zhejiang Provincial Natural Science Foundation of China(LY23C140006);National Natural Science Foundation of China(31901954);Ningbo Natural Science Foundation(2021J126,2023J382);China Agriculture Research System of MOF and MARA(CARS-03)。; Histone acetylation is involved in chromatin structural remodeling and the regulation of gene expression, and it is important for the activation of defense-related gene expression in eukaryotes[1]. The silent informat...; 关键词：IMMUNITY initially ACETYLATION

Functions and mechanisms of non-histone protein acetylation in plants^(∞): 《Journal of Integrative Plant Biology》2024年第10期2087-2101,共15页Xia Jin Xiaoshuang Li Jaime A.Teixeira da Silva Xuncheng Liu; supported by grants from the National Natural Science Foundation of China (No. 32070551 and No. 32371326);the Youth Innovation Promotion Association, CAS (No. 201860);Key Research Program of Frontier Sciences, Chinese Academy of Sciences (ZDBS-LY-SM009)。; Lysine acetylation, an evolutionarily conserved post-translational protein modification, is reversibly catalyzed by lysine acetyltransferases and lysine deacetylases. Lysine acetylation, which was first discovered on ...; 关键词：acetylomics lysine acetylation lysine deacetylation non-histone acetylation post-translational modification

TIP60 acetylation of Bub1 regulates centromeric H2AT120 phosphorylation for faithful chromosome segregation: 《Science China(Life Sciences)》2024年第9期1957-1969,共13页Mengjie Sun Biying Yang Guangwei Xin Yao Wang Jia Luo Qing Jiang Chuanmao Zhang; supported by grants from the National Natural Science Foundation of China(32130026,92254305 and 32070714)。; Proper function of the centromeres ensures correct attachment of kinetochores to spindle microtubules and faithful chromosome segregation in mitosis.Defects in the integrity and function of centromeres can result in c...; 关键词：ACETYLATION BUB1 TIP60 H2ApT120 chromosome segregation

IL-17 induces NSCLC cell migration and invasion by elevating MMP19 gene transcription and expression through the interaction of p300-dependent STAT3-K631 acetylation and its Y705-phosphorylation: 《Oncology Research》2024年第4期625-641,共17页WEN GE YA LI YUTING RUAN NINGXIA WU PEI MA TONGPENG XU YONGQIAN SHU YINGWEI WANG WEN QIU CHENHUI ZHAO; National Natural Science Foundation of China(Grants Numbers 81902878 and 81971468).; The cancer cell metastasis is a major death reason for patients with non-small cell lung cancer(NSCLC).Although researchers have disclosed that interleukin 17(IL-17)can increase matrix metalloproteinases(MMPs)inductio...; 关键词：NSCLC cell migration and invasion IL-17 P300 STAT3 MMP19 Acetylation and phosphorylation

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