supported by grants from the National Natural Science Foundation of China(32130026,92254305 and 32070714)。
Proper function of the centromeres ensures correct attachment of kinetochores to spindle microtubules and faithful chromosome segregation in mitosis.Defects in the integrity and function of centromeres can result in c...
Supported by National Natural Science Foundation of China,No.81550014;Henan Provincial Science and Technology Research Project,No.222102310187 and No.242102310582;Henan Province Postdoctoral Research Project,No.202103092.
BACKGROUND Esophageal carcinoma(EC)is one of the most prevalent cancers in human populations worldwide.Baitouweng decoction is one of the most important Chinese medicine formulas,with the potential to treat cancer.AIM...
supported by the National Natural Science Foundation of China(31970666);Taishan Scholar Project(tsqn201812054)from Shandong,China;Work at the Novo Nordisk Foundation Center for Protein Research was supported by the grant NNF14CC0001;J.N.is supported by grants from the Danish Cancer Society(R269-A15586-B17);Independent Research Fund Denmark(8021-00101B and 0134-00199B);Novo Nordisk Foundation(NNF20OC0065098).
The Bub1 and BubR1 kinetochore proteins support proper chromosome segregation and mitotic checkpoint activity. Bub1 and BubR1 are paralogs with Bub1 being a kinase, while BubR1 localizes the PP2A-B56 protein phosphata...