KINETOCHORES

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相关期刊：《Open Journal of Biophysics》《中国生物学文摘》《Science China(Life Sciences)》《Journal of Molecular Cell Biology》更多>>
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Spatial separation of phosphatase and kinase activity within the Bub complex is required for proper mitosis
《Journal of Molecular Cell Biology》2022年第11期24-35,共12页Lei Wang Thomas Kruse Blanca López-Méndez Yuqing Zhang Chunlin Song Lei Zhu Bing Li Jing Fang Zhimin Lu Jakob Nilsson Gang Zhang 
supported by the National Natural Science Foundation of China(31970666);Taishan Scholar Project(tsqn201812054)from Shandong,China;Work at the Novo Nordisk Foundation Center for Protein Research was supported by the grant NNF14CC0001;J.N.is supported by grants from the Danish Cancer Society(R269-A15586-B17);Independent Research Fund Denmark(8021-00101B and 0134-00199B);Novo Nordisk Foundation(NNF20OC0065098).
The Bub1 and BubR1 kinetochore proteins support proper chromosome segregation and mitotic checkpoint activity. Bub1 and BubR1 are paralogs with Bub1 being a kinase, while BubR1 localizes the PP2A-B56 protein phosphata...
关键词：MITOSIS spindle assembly checkpoint KINETOCHORES BUB1 BUBR1 PP2A/B56 
Electrostatic Mechanism for Depolymerization-Based Poleward Force Generation at Kinetochores
《Open Journal of Biophysics》2019年第3期198-203,共6页L. John Gagliardi Daniel H. Shain 
Experiments implicating bound volume positive charge at kinetochores interacting with negative charge at microtubule free ends have prompted our calculation of the force at kinetochores for chromosome poleward motilit...
关键词：MITOSIS CHROMOSOME MOTILITY Force ELECTROSTATICS 
CENP-K and CENP-H may form coiled-coils in the kinetochores
《Science China(Life Sciences)》2009年第4期352-359,共8页QIU ShuLan, WANG JiaNing, YU Chuang & HE DaCheng The Key Laboratory for Cell Proliferation and Regulation Biology of the Ministry of Education, Beijing Normal University, Universities’ Confederated Institute of Proteomics, Beijing 100875, China 
Supported by the National Key Scientific Program (Grant No. 2006CB910100).
Kinetochores are large proteinaceous structure on the surface of chromosomes’ primary constriction during mitosis. They link chromosomes to spindle microtubules and also regulate the spindle assem- bly checkpoint, wh...
关键词：KINETOCHORE CENP-H CENP-K heterodimeric COILED-COILS 
Human Zwint-1 Specifies Localization of Zeste White 10 to Kinetochores and Is Essential for Mitotic Checkpoint Signaling
《中国生物学文摘》2005年第4期67-75,共9页HongmeiWang XiaoyuHu XiaDing ZhenDou ZhihongYank AndrewW.Shaw MaikunTcng DonW.Cleveland MichaelL.Goldberg LiwenNiu XucbiaoYao 
Chromosome segregation in mitosis is orchestrated by dynamic interaction between spindle microtubules and the kinetochore, a multiprotein complex assembled onto centromeric DNA of the chromosome. Here we show that Zwi...
关键词：染色体 有丝分裂 着丝点 Zwint-1定位 
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