云南高校图书馆联盟文献共享服务平台- PCAF

PCAF: 作品数：34被引量：56H指数：5; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：胡卫列张乐侯继申辛国华梁宗英更多>>; 相关机构：中国科学技术大学广州军区广州总医院北京大学承德医学院附属医院更多>>; 相关期刊：《当代金融家》《科学新闻》《肿瘤防治研究》《中国细胞生物学学报》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划承德市科学技术研究与发展计划项目中国博士后科学基金更多>>

PCAF碳核算方法在商业银行的实践与挑战: 《国际金融》2025年第2期73-80,共8页杜涵肖颖琪; 作为重要的金融媒介之一,商业银行是助力经济可持续发展的关键参与者。对商业银行资产端开展碳核算工作,是商业银行管理碳足迹、开展转型风险分析并推进气候信息披露等工作的重要基础。本文阐述了在银行业应用PCAF方法开展碳核算的价值...; 关键词：PCAF 碳核算碳足迹商业银行气候风险

PCAF-mediated acetylation of METTL3 impairs mRNA translation efficiency in response to oxidative stress: 《Science China(Life Sciences)》2024年第10期2157-2168,共12页Cheng Liu Miao Yu Mengyuan Wang Siyuan Yang Yenan Fu Lei Zhang Chaoyang Zhu Hongquan Zhang; supported by the National Key Research and Development Program of China(2022YFA1104003,2021YFC2501003);the National Natural Science Foundation of China(82230094,81972616,81730071);Peking University Medicine Sailing Program for Young Scholars'Scientific&Technological Innovation(BMU2024YFJHPY004);the Fundamental Research Funds for the Central Universities。; METTL3 methylates RNA and regulates the fate of mRNA through its methyltransferase activity.METTL3 enhances RNA translation independently of its catalytic activity.However,the underlying mechanism is still elusive.Her...; 关键词：METTL3 ACETYLATION PCAF m^(6)A oxidative stress TRANSLATION SIRT3

MZF1(Myeloid Zinc Finger 1)activates transcriptional activity of p53 and suppresses breast cancer cell proliferation via acetyltransferase PCAF(P300/CBP associated factor): 《Genes & Diseases》2023年第5期1775-1778,共4页Bowen Li Shujing Li Xiaoxia Shi Yini Zhang Zhiqiang Xin Yuxi Yang Binggong Zhao Ping Ren Huijian Wu; supported by grants(No.81872263 to H.W.)from the National Natural Science Foundation of China.; p53 is an important tumor suppressor gene.The p53 pathway is activated in response to cellular stress stimulation.However,in more than 50%of breast cancers,p53 is mutated or inactivated,which permits cancer growth.1 A...; 关键词：SCAN Zinc P53

Uncovering the IL-1β-PCAF-NNT axis:A new player in ferroptosis and tumor immune evasion: 《Cancer Communications》2023年第9期1048-1050,共3页Qidong Li Boyi Gan; University of Texas MD Anderson Cancer Center,National Institutes of Health,Grant/Award Numbers:R01CA181196,R01CA244144,R01CA247992,R01CA269646,U54CA274220;Cancer Prevention&Research Institute of Texas,Grant/Award Numbers:RP220258,RP230072;Cancer Center Support,Grant/Award Number:P30 CA016672;National Cancer Institute。; Chronic inflammation is recognized as a crucial hallmark of cancer.Interleukin-1β(IL-1β),one of the proinflammatory cytokines,plays an ambiguous or even contradictory role in cancer development[1].While increased ex...; 关键词：tumor inflammation INTERLEUKIN

PCAF碳核算应用于碳减排支持工具的思考: 《当代金融家》2023年第1期52-54,共3页边赛; 碳核算金融联盟(PCAF)是一项由金融行业主导的全球性碳核算联盟,致力于协助金融机构衡量和披露其投资的温室气体排放量。其目标是推动金融领域碳排放核算和披露标准化,并协助金融部门与《巴黎气候协议》要求保持一致。; 关键词：金融机构碳核算温室气体排放量行业主导支持工具碳减排碳排放核算金融领域

食管癌ABCE1乙酰化与KAT5、p300/CBP及PCAF表达相关性及临床意义: 《肿瘤学杂志》2022年第2期122-127,共6页梁宗英张乐赵宝山侯继申辛国华; 河北省医学科学研究重点课题计划项目(20181159)。; [目的]探讨ABCE1乙酰化与乙酰基转移酶KAT5、p300/CBP及PCAF在食管癌中的表达相关性及其临床意义。[方法]选择70例食管鳞癌组织及其癌旁食管黏膜组织,采用免疫共沉淀检测组织中ABCE1乙酰化水平,qRT-PCR检测KAT5、p300/CBP及PCAF组织中m...; 关键词：食管肿瘤 ABCE1 乙酰化乙酰基转移酶临床意义

P300/CBP-associated factor(PCAF)-mediated acetylation of Fascin at lysine 471 inhibits its actin-bundling activity and tumor metastasis in esophageal cancer被引量：2: 《Cancer Communications》2021年第12期1398-1416,共19页Yin-Wei Cheng Fa-Min Zeng Da-Jia Li Shao-Hong Wang Jian-Zhong He Zhen-Chang Guo Ping-Juan Nie Zhi-Yong Wu Wen-Qi Shi Bing Wen Xiu-E Xu Lian-Di Liao Zhi-Mao Li Jian-Yi Wu Jun Zhan Hong-Quan Zhang Zhi-Jie Chang Kai Zhang Li-Yan Xu En-Min Li; National Natural Science Foundation of China,Grant/Award Numbers:81872372,81902469;Natural Science Foundation of China-Guangdong Joint Fund,Grant/Award Number:U0932001;National Cohort of Esophageal Cancer of China,Grant/Award Number:2016YFC0901400;China Postdoctoral Science Foundation,Grant/Award Number:2018M643134;2020 Li Ka Shing Foundation Cross-Disciplinary Research Grant,Grant/Award Number:2020LKSFG07B。; Background:Fascin is crucial for cancer cell filopodium formation and tumor metastasis,and is functionally regulated by post-translational modifications.However,whether and how Fascin is regulated by acetylation remai...; 关键词：ACETYLATION actin-bundling esophageal cancer FASCIN filopodium formation P300/CBPassociated factor(PCAF) tumor metastasis

PCAF and SIRT1 modulateβTrCP1 protein stability in an acetylation-dependent manner: 《Journal of Genetics and Genomics》2021年第7期652-655,共4页Fabin Dang Cong Jiang Tao Zhang Hiroyuki Inuzuka Wenyi Wei; supported in part by 1K99CA263194 to F.D.,R01CA229307,R35CA253027 to W.W。; Ubiquitination plays critical roles in regulating various physiological events,such as protein degradation,activation,secretion,sorting and trafficking(Dang et al.,2021).The ubiquitination process involves three major...; 关键词：STABILITY STEPS CATALYZED

原发性肝癌淋巴结转移临床病理特点与预后的关系: 《中国保健食品》2021年第2期122-123,共2页马付国张伟鹏牛广旭; 目的:原发性肝癌的恶性较高,初期缺少临床上的明显症状,一旦发现一般都是中晚期,使得其在治疗上的效果和预后并不是十分的理想。所以,控制原发性肝癌在治疗之后的相关因素,是目前临床上对于患者预后给予改善的一个非常必要的途径。本研...; 关键词：原发性肝癌 SKP2 p27 p-Catenin PCAF 临床病理特征预后因素 COX回归

食管癌Survivin乙酰化水平与PCAF P300表达的相关性及临床意义被引量：6: 《河北医学》2019年第8期1377-1380,共4页赵宝忠侯继申张乐孙光蕊辛国华梁宗英; 2016年承德市科学技术研究与发展计划项目,(编号:201606A036); 目的:探讨食管癌组织中Survivin蛋白的乙酰化水平与PCAF、P300及临床病例特征之间的关系.方法:采用免疫共沉淀检测70例食管癌和癌旁正常食管组织中Survivin蛋白乙酰化水平;免疫组化法检测PCAF、p300在食管癌组织中的表达水平;分析Survi...; 关键词：SURVIVIN PCAF P300 乙酰化食管癌

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