supported by grants from the Tianjin Health Technology Project(Grant no.2022QN106).
Background:The Fascin(FSCN)family,comprising actin-bundling proteins,plays vital roles in cytoskeletal reorganization and cell migration.FSCN1,FSCN2,and FSCN3 are implicated in cancer progression through cell motility...
supported by the grant from the National Science Foundation of China(No.82002075).
Diabetic nephropathy(DN)is the main cause of end-stage renal disease worldwide.It is reported that the endothelial-to-mesenchymal transition(EndMT)in glomerular endothelial cells plays an important role in DN.As a spe...
supported by the grants from the National Natural Science Foundation of China(81872372);the Guangdong Basic and Applied Basic Research Foundation(2020A1515011532);the Natural Science Foundation of China-Guangdong Joint Fund(U0932001);the National Cohort of Esophageal Cancer of China(2016YFC0901400);the China Postdoctoral Science Foundation(2018M643134);2020 Li Ka Shing Foundation Cross-Disciplinary Research Grant(2020LKSFG07B).
Dear Editor,Fascin actin-bundling protein 1(Fascin,gene name:FSCN1)is the primary actin-bundling protein that clusters filaments into stable and bundled filopodia[1].In previous studies,elevated levels of Fascin promo...