国家自然科学基金(30400191)

作品数：14被引量：66H指数：5
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相关机构：江苏省人民医院南京医科大学东南大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《Chinese Medical Journal》《国际呼吸杂志》《中国呼吸与危重监护杂志》更多>>
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Inhibitory effects of sunitinib on ovalbumin-induced chronic experimental asthma in mice被引量：5
《Chinese Medical Journal》2009年第9期1061-1066,共6页HUANG Mao LIU Xuan DU Qiang YAO Xin YIN Kai-sheng 
This work was supported by a grant from the National Natural Science Foundation of China （No. 30400191）.
Background Tyrosine kinase signaling cascades play a critical role in the pathogenesis of allergic airway inflammation. Sunitinib, a multitargeted receptor tyrosine kinase inhibitor, has been reported to exert potent ...
关键词：ASTHMA airway remodeling tyrosine kinase inhibitor SUNITINIB 
Expression of surface markers on peripheral CD4＋CD25^high T cells in patients with atopic asthma： role of inhaled corticosteroid被引量：10
《Chinese Medical Journal》2008年第3期205-212,共8页ZHANG Qian QIAN Fen-hong LIU Hua ZHOU Lin-fu HUANG Mao ZHANG Xi-long YIN Kai-sheng 
ZHANG Qian and QIAN Fen-hong equally contributed to this work. This study was supported by the grants from the National Natural Science Foundation of China （No. 30400191 and 30570797）, Key Subject of Project ＂135＂ of Jiangsu Province （No. 20013102） and Summit Project of Jiangsu Human Resources （No. 06B035）.
Background CD4^＋CD25^＋ regulatory T cells （Tregs） mediate immune suppression through cell-cell contact with surface molecules, particularly cytotoxic T lymphocyte-associated antigen 4 （CTLA-4）, glucocorticoid-in...
关键词：ASTHMA ATOPY GLUCOCORTICOIDS regulatory T cells transforming growth factor β 
Effects of adenoviral gene transfer of mutated IκBα,a novel inhibitor of NF-κB,on human monocyte-derived dendritic cells被引量：1
《Acta Pharmacologica Sinica》2006年第5期609-616,共8页Lin-fu ZHOU Ming-shun ZHANG Kai-sheng YIN Yong JI Wei-ping XIE Xue-fan CUI Xiao-hui JI 
Project supported by grants from the National Youth Natural Science Foundation of China(No 30400191);National Natural Science Foundation of China(No 30570797);the Key Subject of Project "135" of Jiangsu Province(No 20013102).
Aim： To investigate the effects of adenoviral gene transfer of IκBα mutant （IκBαM）, a novel inhibitor of nuclear factor κB （NF-κB）, on apoptosis, phenotype and function of human monocyte-derived dendritic c...
关键词：dendritic cells nuclear factor κB IxBα mutant IMMUNOTHERAPY ASTHMA 
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