云南高校图书馆联盟文献共享服务平台- 国家自然科学基金(81230041)

国家自然科学基金(81230041): 作品数：18被引量：71H指数：5; 导出分析报告; 相关作者：付小兵张翠萍赵洪良陈艳谭志军更多>>; 相关机构：解放军总医院第一附属医院天津医科大学中国人民解放军总医院石家庄市第一医院更多>>; 相关期刊：《Burns & Trauma》《亚洲外科手术病例研究》《Science China(Life Sciences)》《中华实验外科杂志》更多>>; 相关主题：IN_CHINASTEM_CELLTISSUE_ENGINEERINGMICROENVIRONMENT创面修复更多>>; 相关领域：医药卫生生物学环境科学与工程经济管理更多>>

成簇规律间隔短回文重复序列及其相关蛋白基因9系统在干细胞研究中的应用进展: 《中华烧伤杂志》2018年第4期253-256,共4页孙苏静霍嘉慧耿志军孙晓艳付小兵; 国家自然科学基金（81121004、81230041、81421064、81372067）; 随着对DNA碱基精确识别的核酸酶研究的深入，第3代基因编辑技术，如锌指核酸酶（ZFN）技术、类转录激活因子样效应物核酸酶（TALEN）技术等发展迅速，由于该类技术能够精确地进行DNA水平的特定位点敲除、插入及替换，加深研究者对生物...; 关键词：干细胞成簇规律间隔短回文重复序列及其相关蛋白基因9 基因编辑

上皮-间质转化在皮肤创面修复中作用的研究进展: 《中华创伤杂志》2017年第10期949-953,共5页霍嘉慧孙苏静耿志军李想孙晓艳马奎付小兵; 国家自然科学基金（30901564,81101883,81245185,81372067,81121004,81230041）;国家重点基础研究发展计划（“973”计划）（2012CB518105）; 上皮一间质转化（ epithelial - mesenchymal transition，EMT）最早的描述见于19世纪60年代Trelstad等。发现在鸡胚胎形成过程中，单胚层重组为三层结构，此过程也被称为原肠胚形成。随后，Greenburg和Hay提出了EMT的概念，即上皮细胞...; 关键词：上皮-间质转化创面修复皮肤器官纤维化 EMT 胚胎形成三层结构细胞极性

Mesenchymal stem cells-derived exosomal microRNAs contribute to wound inflammation被引量：28: 《Science China(Life Sciences)》2016年第12期1305-1312,共8页Dongdong Ti Haojie Hao Xiaobing Fu Weidong Han; supported by the National Basic Science and Development Program(2012CB518103,2012CB518105);National High Technology Research and Development Program of China (2013AA020105,2012AA020502);National Natural Science Foundation of China(81121004,81501682,81230041); Clinical and experimental studies have highlighted the significance of inflammation in coordinating wound repair and regeneration.However,it remains challenging to control the inflammatory response and tolerance at sy...; 关键词：microRNA INFLAMMATION mesenchymal stem cell EXOSOME

Dynamic microenvironment and multiple damaged tissue regeneration in a de novo and synchronized manner: 《Science China(Life Sciences)》2016年第12期1332-1334,共3页Biao Cheng Xiaobing Fu; supported in part by the National Nature Science Foundation of China (81121004, 81230041, 81171798, 81171812, 81272105, 81671924);the National Basic Science and Development Programme (2012CB518105);the National Science and Technology Major Project (2011ZXJ07104B-03B); Regenerative medicine has rapidly developed over the past decade and created new opportunities to repair or replace tissue or organ function lost because of congenital defects, age, diseases, or serious damage （Cheng...; 关键词：CELL Dynamic microenvironment and multiple damaged tissue regeneration in a de novo and synchronized manner

Skin appendage-derived stem cells: cell biology and potential for wound repair被引量：3: 《Burns & Trauma》2016年第4期258-263,共6页Jiangfan Xie Bin Yao Yutong Han Sha Huang Xiaobing Fu; This paper was supported in part by the National Nature Science Foundation of China(81121004,81230041,81372066,81571909);the National Basic Science and Development Program(973 Program,2012CB518105); Stem cells residing in the epidermis and skin appendages are imperative for skin homeostasis and regeneration.These stem cells also participate in the repair of the epidermis after injuries,inducing restoration of tis...; 关键词：Skin appendages Stem cells Cell biology Wound healing

Innovative and propagable translational research model established for cell-based therapy at Chinese PLA General Hospital被引量：1: 《Science China(Life Sciences)》2016年第10期1063-1067,共5页Weidong Han Xiaobing Fu; supported by the National Natural Science Foundation of China(81230061,81121004,and 81230041);the Military Medical Foundation(AWS11J008);the National Basic Research Program of China(2012CB518105); The use of translational medicine in Chinese hospitals ap- pears to have become easier over the last decade. Products developed in the laboratory can sometimes be applied in the clinic under life-saving circumstances....; 关键词：中国人民解放军细胞疗法转化医院模型创新实验室应用

Regenerative medicine in China:demands, capacity,and regulation被引量：2: 《Burns & Trauma》2016年第2期71-77,共7页Biao Cheng Shuliang Lu Xiaobing Fu; This study was supported in part by the National Nature Science Foundation of China(81121004,81230041,81171812,81272105,and 81171798);the National Basic Science and Development Programme(973 Program,2012CB518105);National Science and Technology Major Project(2011ZXJ07104B-03B); Regenerative medicine(RM)is an emerging interdisciplinary field of research.Its clinical application focuses on the repair,replacement,and regeneration of cells,tissues,and organs by approaches including cell reprogra...; 关键词：Regenerative medicine Stem cell Tissue engineering China

Regenerative medicine in China:main progress in different fields被引量：5: 《Journal of Medical Colleges of PLA(China)》2016年第3期140-152,共13页Biao Cheng Shu-Liang Lu Xiao-Bing Fu; supported by the National Nature Science Foundation of China(81171812,81272105,81121004,81230041,and 81171798);the National Basic Science and Development Programme(973 Programme,2012CB518105);the National Science and Technology Major Project(2011ZXJ07104B-03B);the Health and Medical Treatment Collaborative Innovation Major Special Projects of Guangzhou(No.201508020253);the Science and Technology Key Project of Guangdong Province(2014B020212010); Regenerative medicine(RM) is an emerging interdisciplinary field of research and China has developed the research quickly and impressed the world with numerous research findings in stem cells,tissue engineering,active...; 关键词：Regenerative medicine Stem cells Tissue engineering China

激动素在创面修复及皮肤美容中作用的研究进展被引量：2: 《中华创伤杂志》2015年第12期1135-1138,共4页周云超赵志力张翠萍付小兵; 国家重点基础研究发展计划资助项目（2012CB518105）;国家自然科学基金资助项目（81121004,81230041,81171798,30973123）; 激动素（kinetin，KT）是60年前发现的第一个细胞分裂素，经过国内外60年的不断研究，人们对它的观念已从最初的定义植物激素逐步发展为对动植物及人体起广泛作用的物质，并已把它应用于皮肤的美容护理和人体疾病的治疗。然而，KT对动...; 关键词：皮肤美容激动素创面修复细胞分裂素植物激素人体疾病美容护理归纳总结

人骨髓间充质干细胞与其来源的汗腺样细胞微小RNAs差异表达谱分析被引量：3: 《中华医学杂志》2015年第32期2626-2629,共4页谭志军陈艳赵洪良赵换军赵阿龙赵智亮孙梦黎马奎张翠萍付小兵; 国家自然科学基金（81421064,81230041,81171798）; 目的分析入骨髓间充质干细胞（hBM-MSCs）与其来源的汗腺样细胞微小RNAs（miRNAs）差异表达谱.方法采用成骨、成脂细胞诱导分化液诱导hBM-MSCs分化,油红O和茜素红染色分别进行鉴定.当原代汗腺细胞密度达到70％～ 80％时进行热休克处理...; 关键词：间质干细胞汗腺微RNAS 基因表达谱

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