supported by the National Basic Research Program of China(973Program,2011CB910404 and 2012CB966800);China National Natural Science Foundation(30901432 and 30972949);the Chinese Ministry of Education(109056);Program for New Century Excellent Talents in University Award(NCET-08-0131);Shanghai Science and Tech-nology Committee(11DZ2211000).
Metastasis is a very complicated multi-step process and accounts for the low survival rate of the cancerous patients.To metastasize,t he malignant cells must detach from the primary tumor and migrate to secondary site...
supported by grants from the National Key Sci-Tech Special Project of China(2008ZX10002-018/019);the Shanghai Rising-Star Program(10QA1401300);the National Natural Science Foundation of China(30901432);the Research Fund for the Doctoral Program of Higher Education of China (20090071120026)
BACKGROUND:In vitro experiments and mice models have confirmed the importance of Sprouty 2(Spry2) in inhibiting tumorigenesis and the progression of human cancer.However,the prognostic value of Spry2 in cancer patient...