Supported by the National Natural Science Foundation of China(Nos20225102, 20331020, 20325101 and 20473084);Hundred People Program of Chinese Academy of Sciences
p21^wafl/cipl, best known as a broad-specificity inhibitor of cyclin/cyclin-dependent kinase complexes, can interact with various target proteins, and this ability relies on its structural plasticity. Therefore, studi...
Supported by the National Natural Science Foundation of China (Grant No. 20331020) ;985 Program and Beijing City Research Programs of Science & Technology
Several vanadium compounds have been known for the hypoglycemic and anticancer effects. However, the mechanisms of the pharmacological and toxicological effects were not clear. In this work, we in- vestigated the pote...
采用电子光谱、荧光光谱、循环伏安法研究了[Cu(phendio)(L-Phe)(H_2O)](ClO_4)·H_2O(简称CuPP,phendio=1,10-菲咯啉-5,6-二酮,L-Phe=L-苯丙氨酸)和小牛胸腺 DNA 之间的相互作用.结果表明,当加入一定量的 DNA 时,电子光谱的最大吸收峰...
Aim Cysteine proteases are closely associated with many human and non-human pathological processes and are potential targets for metal ions especially Hg^2+ and the related species. In the present work, on the basis ...