the financial support from the National Natural Science Foundation of China (Nos. 21172093, 31070708, and 21072075);the Natural Science Foundation of Jilin Province of China (Nos. 201115039 and 20140101141JC);the Scientific Research Fund of Jilin University (No. 450060326007)
A simple and efficient Knoevenagel condensation between a b-unsaturated aldehydes and active methylene compounds is reported.Notably,this condensation can be catalyzed by PPL(lipase from porcine pancreas) with satis...
Supported by the National Natural Science Foundation of China(Nos.20772046, 21072075)
Acyl-peptide releasing enzyme(AARE) belongs to a serine peptidase family and catalyzes the NH2-terminal hydrolysis of Nα-acylpeptides to release Nα-acylated amino acids. ORF0779(ORF=open reading frame) from ther...
Supported by the National Natural Science Foundation of China(Nos.30870539, 21072075);the 38th Postdoctoral Foundation of China(No.801050321413)
The stereospecific hydrolysis of mandelate can be effectively catalyzed by hyperthermophilic acylpeptide esterase APE 1547(Aeropyrum pernix esterase 1547). APE 1547 used in this reaction showed a remarkable stereodi...