Acknowledgements This work was supported by grants from the Ministry of Science and Technology of China (No 2010CB912601, 2006CB503804, 2009ZX09303-006, 2009ZX09301-011), the National Natural Science Foundation of China (No 30825016, 30971064), the Science and Technology Commission of Shang- hai Municipality (No 09XD1400400, 08JC1401400) and College Natural Science Research Foundation of Jiangsu Province (No 07KJD310171). We would like to thank Dr Peter ROSE for critical comments regarding this manuscript.
Aim: To examine the effects of all-trans retinoic acid (atRA) on renal morphology and function as well as on renal plasminogen activator inhibitor-1 (PAl-1) expression and plasmin activity in rats with 5/6 nephre...