云南高校图书馆联盟文献共享服务平台- PLASMIN

PLASMIN: 作品数：21被引量：65H指数：4; 导出分析报告; 相关作者：张建华陈家树邢苗欧阳秋玲梁秀霞更多>>; 相关机构：四川大学中山医科大学深圳市微生物基因工程重点实验室深圳大学更多>>; 相关期刊：《Chinese Journal of Cancer Research》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Chinese Medical Journal》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金更多>>

L-Palmitoylcarnitine potentiates plasmin and tPA to inhibit thrombosis: 《Natural Products and Bioprospecting》2023年第1期171-180,共10页Juan Yang Lina Cha Yepeng Wang Quan Zhang Xiaopeng Tang Jianlin Shao Zilei Duan; Priority Union Foundation of Yunnan Provincial Science and Technology Department and Kunming Medical University(202101AC070461).; L-Palmitoylcarnitine(L-PC)is an important endogenous fatty acid metabolite.Its classical biological functions are involved in the regulations of membrane molecular dynamics and theβ-oxidation of fatty acids.Decreased...; 关键词：L-palmitoylcarnitine COAGULATION PLASMIN Tissue-type plasminogen activator THROMBOSIS

The uPA/uPAR system in astrocytic wound healing被引量：1: 《Neural Regeneration Research》2022年第11期2404-2406,共3页Manuel Yepes; National Institutes of Health Grant NS-091201(to MY);VA MERIT Award I01BX003441(to MY)。; The repair of injured tissue is a highly complex process that involves cell prolife ration,differentiation,and migration.Cell migration requires the dismantling of intercellular contacts in the injured zone and their ...; 关键词：ASTROCYTES lipoprotein receptor-related protein 6 PLASMIN urokinase receptor urokinase-type plasminogen activator Wnt-β-catenin pathway wound healing Β-CATENIN

The plasminogen activating system in the pathogenesis of Alzheimer’s disease被引量：4: 《Neural Regeneration Research》2021年第10期1973-1977,共5页Manuel Yepes; This work was supported in part by National Institutes of Health Grant NS-NS091201(to MY)and VA MERIT Award IO1BX003441(to MY).; Dementia is a clinical syndrome that affects approximately 47 million people worldwide and is characterized by progressive and irreversible decline of cognitive,behavioral and sesorimotor functions.Alzheimer’s diseas...; 关键词：Alzheimer’s disease amyloid precursor protein amyloidβ NEUROSERPIN PLASMIN plasminogen activating system plasminogen activator inhibitor-1 synapse tissue-type plasminogen activator urokinase-type plasminogen activator

Using antifibrinolytics to tackle neuroinflammation被引量：1: 《Neural Regeneration Research》2020年第12期2203-2206,共4页Stanimir Atsev Nikola Tomov; Plasmin is generally known as a promotor of inflammation.Recent advancement suggests that it has a complex role as immunity modulator.Pharmacological inhibition of plasmin production and activity has been proven to im...; 关键词：antifibrionolytics FIBRIN fibrinogen NEUROINFLAMMATION PLASMIN PLASMINOGEN tranexamic acid

Regulation of macrophage activation in the liver after acute injury: Role of the fibrinolytic system被引量：3: 《World Journal of Gastroenterology》2020年第16期1879-1887,共9页Katherine Roth Jenna Strickland Bryan L Copple; Supported by National Institutes of Health Grant,No.DK073566(to Copple BL);National Institutes of Health Training Grant,No.ES007255(to Roth K and Strickland J).; The liver functions,in part,to prevent exposure of the body to potentially harmful substances ingested in the diet.While it is highly efficient at accomplishing this,it is frequently prone to liver injury due to the b...; 关键词：MACROPHAGE PLASMIN ACETAMINOPHEN LIVER INJURY LIVER REPAIR

Annexin A2-S100A10 heterotetramer is upregulated by PML/RARα fusion protein and promotes plasminogen-dependent fibrinolysis and matrix invasion in acute promyelocytic leukemia被引量：4: 《Frontiers of Medicine》2017年第3期410-422,共13页Dan Huang Yan Yang Jian Sun Xiaorong Dong Jiao Wang Hongchen Liu Chengquan Lu Xueyu Chen Jing Shao Jinsong Yan; Aberrant expression of annexin A2-SI00A10 heterotetramer （AIIt） associated with PML/RARα fusion protein causes lethal hyperfibrinolysis in acute promyelocytic leukemia （APL）, but the mechanism is unclear. To faci...; 关键词：annexin A2-S100A10 heterotetramer PML/R.ARa fusion protein PLASMIN cell invasion acute promyelocytic leukemia

Tissue-type plasminogen activator is a homeostatic regulator of synaptic function in the central nervous system被引量：1: 《Neural Regeneration Research》2017年第3期362-365,共4页Valerie Jeanneret Manuel Yepes; supported in part by National Institutes of Health Grants NS-079331(to MY)and NS-091201(to MY); Membrane depolarization induces the release of the serine proteinase tissue-type plasminogen activator（t PA） from the presynaptic terminal of cerebral cortical neurons.Once in the synaptic cleft this t PA promotes t...; 关键词：tissue-type plasminogen activator （tPA） homeostatic plasticity Ca^2＋/calmodulin-dependent protein kinase post-synaptic density protein phosphatase 1 PLASMIN

Sulodexide and Alzheimer’s Disease: A Preliminary Prospective Study: 《World Journal of Cardiovascular Diseases》2016年第2期54-71,共18页Joaquín Lasierra-Cirujeda María José Aza Pascual-Salcedo María Mercedes Aza Pascual-Salcedo; The purpose of this prospective study is to determine the relative incidence of Alzheimer’s disease in patients treated for at least three years, with sulodexide (n = 46, 76.48 ± 7.02 years old) or acenocoumarol (n ...; 关键词：SULODEXIDE Alzheimer’s Disease GLUTATHIONE t-PA PAI-1 PLASMINOGEN PLASMIN

Osteopontin is an important mediator of alcoholic liver disease via hepatic stellate cell activation被引量：6: 《World Journal of Gastroenterology》2014年第36期13088-13104,共17页Devanshi Seth Alastair Duly Paul C Kuo Geoffrey W McCaughan Paul S Haber; Supported by Philanthropic Anonymous Source;the University of Sydney Bridging Support Grant,in part for Honours Project;Supported by the National Health and Medical Research Council,No.NHMRC Practitioner Research Fellowship for PH support; AIM: To investigate over-expression of Osteopontin (OPN) pathway expression and mechanisms of action in human alcoholic liver disease (ALD), in vivo and in vitro acute alcohol models.; 关键词：Hepatic stellate cells Liver cirrhosis PLASMIN STEATOSIS FIBROGENESIS Transforming growth factor β Osteopontin isoform

Recruitment of CCR6-expressing Thl7 cells by CCL20 secreted from plasmin-stimulated macrophages被引量：8: 《Acta Biochimica et Biophysica Sinica》2013年第7期593-600,共8页Qun Li Yves Laumonnier Tatiana Syrovets Thomas Simmet; This work was supported by the grants from the Deutsche Forschungs gemeinschaft （to T.S. and T.S.）, the Shanghai Scientific Research Innovation Program （11YZ59 to Q.L.）, the Shanghai Pujiang Program （10PJ1407300 to Q.L.）, the New Scholar Programs Foundation of Ministry of Education of China （20110073120103 to Q.L.）, and the National Natural Science Foundation of China （81202298 to Q.L.）.; In the present study, monocyte-derived human macro-phages were differentiated from buffy coats. Naive CD^4＋ T-cells enriched from peripheral blood mononuclear cells using anti-CD4 magnetic beads and the autoMACS sepa...; 关键词：PLASMIN MACROPHAGES signaling CCL20 Thl 7 CCR6

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