云南高校图书馆联盟文献共享服务平台- PLASMINOGEN

PLASMINOGEN: 作品数：187被引量：985H指数：13; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：史晨辉王英郝利赵秋菊朱勤忠更多>>; 相关机构：复旦大学石河子大学医学院第一附属医院首都医科大学宣武医院浙江大学医学院附属第二医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金浙江省医药卫生科学研究基金World Health Organization广西壮族自治区自然科学基金更多>>

The emerging role of tranexamic acid and its principal target,plasminogen,in skeletal health: 《Acta Pharmaceutica Sinica B》2024年第7期2869-2884,共16页Weixin Xie Antonia Donat Shan Jiang Anke Baranowsky Johannes Keller; supported by the German Research Foundation(KE 2179/9-1,Germany).; The worldwide burden of skeletal diseases such as osteoporosis,degenerative joint disease and impaired fracture healing is steadily increasing.Tranexamic acid(TXA),a plasminogen inhibitor and anti-fibrinolytic agent,i...; 关键词：Tranexamic acid OSTEOPOROSIS OSTEOARTHRITIS Fracture healing Bone metabolism INFLAMMATION PLASMINOGEN FIBRINOLYSIS

A novel plasminogen mutation in a child with hereditary periodic syndrome: A case report: 《Rheumatology & Autoimmunity》2022年第4期237-243,共7页Lujayn Akbar Anas M.Alazami Alhanouf AlSaleem Abdullah Alsonbul Sulaiman M.Al‐Mayouf; Introduction:Plasminogen(PLG)deficiency is an ultrarare disease.The reported manifestations in literature were linked to pseudomembrane formation and mucosal surfaces inflammation.Recently,PLG,its activa-tors and its ...; 关键词：autoinflammatory disease familial Mediterranean fever MEFV gene PLASMINOGEN PLG mutation

The plasminogen activating system in the pathogenesis of Alzheimer’s disease被引量：4: 《Neural Regeneration Research》2021年第10期1973-1977,共5页Manuel Yepes; This work was supported in part by National Institutes of Health Grant NS-NS091201(to MY)and VA MERIT Award IO1BX003441(to MY).; Dementia is a clinical syndrome that affects approximately 47 million people worldwide and is characterized by progressive and irreversible decline of cognitive,behavioral and sesorimotor functions.Alzheimer’s diseas...; 关键词：Alzheimer’s disease amyloid precursor protein amyloidβ NEUROSERPIN PLASMIN plasminogen activating system plasminogen activator inhibitor-1 synapse tissue-type plasminogen activator urokinase-type plasminogen activator

Using antifibrinolytics to tackle neuroinflammation被引量：1: 《Neural Regeneration Research》2020年第12期2203-2206,共4页Stanimir Atsev Nikola Tomov; Plasmin is generally known as a promotor of inflammation.Recent advancement suggests that it has a complex role as immunity modulator.Pharmacological inhibition of plasmin production and activity has been proven to im...; 关键词：antifibrionolytics FIBRIN fibrinogen NEUROINFLAMMATION PLASMIN PLASMINOGEN tranexamic acid

Urokinase-type plasminogen activator is a modulator of synaptic plasticity in the central nervous system:implications for neurorepair in the ischemic brain被引量：10: 《Neural Regeneration Research》2020年第4期620-624,共5页Manuel Yepes; supported in part by National Institutes of Health Grant NS-091201(to MY);VA MERIT Award IO1BX003441(to MY); The last two decades have witnessed a rapid decrease in mortality due to acute cerebral ischemia that paradoxically has led to a rapid increase in the number of patients that survive an acute ischemic stroke with vari...; 关键词：cerebral ischemia NEUROREPAIR PLASMINOGEN plasticity stoke SYNAPSE UROKINASE UROKINASE receptor

Inhibiting endogenous tissue plasminogen activator enhanced neuronal apoptosis and axonal injury after traumatic brain injury被引量：10: 《Neural Regeneration Research》2020年第4期667-675,共9页Jun-Jie Zhao Zun-Wei Liu Bo Wang Ting-Qin Huang Dan Guo Yong-Lin Zhao Jin-Ning Song; Tissue plasminogen activator is usually used for the treatment of acute ischemic stroke,but the role of endogenous tissue plasminogen activator in traumatic brain injury has been rarely reported.A rat model of traumat...; 关键词：apoptosis ASTROCYTES AXONAL INJURY inflammation microglia nerve REGENERATION neural REGENERATION neuronal INJURY neurons NEUROSERPIN tissue PLASMINOGEN activator traumatic brain INJURY

An update on the genetics and pathogenesis of hereditary angioedema被引量：2: 《Genes & Diseases》2020年第1期75-83,共9页Aaqib Zaffar Banday Anit Kaur Ankur Kumar Jindal Amit Rawat Surjit Singh; Hereditary angioedema(HAE)is an uncommon genetic disorder characterized by recurrent episodes of edema involving subcutaneous tissue and submucosa.The pathogenesis of HAE reflects an intricate coordinated regulation o...; 关键词：Angiopoietin 1 C1 inhibitor Factor XII GENETICS Hereditary angioedema PLASMINOGEN

Unlikely role of glycolytic enzyme α-enolase in cancer metastasis and its potential as a prognostic biomarker被引量：2: 《Journal of Cancer Metastasis and Treatment》2020年第1期97-108,共12页Lachlan Schofield Lisa F.Lincz Kathryn A.Skelding; the Calvary Mater Newcastle and Hunter Medical Research Institute.; Reliance on glycolysis for energy production is considered a hallmark of cancer and the glycolytic enzyme a-enolase is overexpressed in a range of cancer types.However,recent studies have revealed that a-enolase is in...; 关键词：ALPHA-ENOLASE ENO1 METASTASIS migration INVASION PROLIFERATION plasminogen-binding receptor

阿替普酶联合尤瑞克林治疗急性脑梗死中的疗效评估被引量：41: 《中华急诊医学杂志》2019年第6期784-786,共3页巩利英张桂茹; 1996年美国食品和药品监督管理局批准重组组织型纤维蛋白酶原激活剂(recombinant tissue plasminogen activator,rt-PA)用于静脉溶栓治疗[1],中国急性缺血性脑卒中诊疗指南2014年版:对发病3 h内的缺血性脑卒中患者,应根据适应证尽快静...; 关键词：静脉溶栓治疗急性脑梗死尤瑞克林阿替普酶疗效评估急性缺血性脑卒中 PLASMINOGEN ACTIVATOR

阿替普酶联合通心络胶囊对老年急性心肌梗死病人临床疗效、心肌损伤标志物及炎症因子水平的影响被引量：23: 《实用老年医学》2019年第1期62-64,共3页邱男安亚平龙永锦邓佳; 急性心肌梗死为老年人常见病,可并发心律失常、休克或心力衰竭,严重危及病人生命健康[1]。尿激酶、链激酶、组织型纤维蛋白溶酶原激活剂(recombinant tissue plasminogen activater,rt-PA)等是溶解血栓常用药物,使闭塞冠脉再通。阿替普...; 关键词：老年急性心肌梗死心肌损伤标志物通心络胶囊临床疗效阿替普酶炎症因子组织型纤维蛋白溶酶原激活剂 PLASMINOGEN

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