supported by the Science and Technology Commission of Shanghai Municipality (grant no.22Y11900300);China Primary Health Care Foundation (grant no.MTP2022A0132);Project of Shanghai Administration of Traditional Chinese Medicine (ZXXT-202213)to EQM and LM。
BACKGROUND:This study aimed to explore the importance of routine coagulation tests for the early detection of sepsis and to quickly identify patients at a high risk of mortality.METHODS:This retrospective single-cente...
supported by the German Research Foundation(KE 2179/9-1,Germany).
The worldwide burden of skeletal diseases such as osteoporosis,degenerative joint disease and impaired fracture healing is steadily increasing.Tranexamic acid(TXA),a plasminogen inhibitor and anti-fibrinolytic agent,i...
BACKGROUND ST-elevation myocardial infarction(STEMI)is the result of transmural ischemia of the myocardium and is associated with a high mortality rate.Primary percutaneous coronary intervention(PPCI)is the recommende...
Background:Reperfusion therapy is fundamental for ST-segment elevation myocardial infarction(STEMI).However,the details of contemporary practice and factors associated with reperfusion therapy in China are largely unk...
funded by the Berta-Ottenstein-Programme for Advanced Clinician Scientists,Faculty of Medicine,University of Freiburg.
Background To compare the efficacy of two different concepts of cisternal therapy—PREVENTIVE fibrinolysis plus on-demand spasmolysis versus RESCUE spasmolysis—for the prevention of cerebral vasospasm(CVS)and delayed...
supported by the National Natural Science Foundation of China(grant nos.51988102,51833007,51690152,51533006,and 21721005);the National Key Research and Development Program of China(grant no.2019YFA0905603).
Tumor vascular infarction has been regarded as a promising therapy in tumor treatment.However,due to the limited activity of designed coagulation agents,resulting from the challenges of inducing sustained and complete...
Treatment of central retinal artery occlusion (CRAO) has been an ambiguous entity in the medical community. Many interventions have been explored;however, a standard of care has yet to be defined. Recent studies have ...
This work was supported by the National Institutes of Health grant number(R01 NS105853).
There has been growing interest and insight into the histological composition of retrieved stroke emboli.One of the main focuses of the stroke clot analysis literature has been the implications of clot composition on ...
Prosthetic valve thrombosis (PVT) is a rare but serious entity. Its diagnosis and treatment can be challenging and mortality remains high regardless of its management. A 50-year-old man admitted with cardiac arrest, w...
supported by the National Natural Science Foundation of China(81773735,81903610,91949130,81961138018);National Key R&D Program of China(2017YFC1702003).
Thrombotic diseases are the leading causes of death worldwide,especially in cold climates.Traditional Chinese medicine(TCM)-based therapies have gained increasing popularity worldwide,but also raised some concerns abo...